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Conservative surgery versus standard care in treating neuropathic plantar forefoot ulcers. A meta-analysis of comparative studies
منشور في 2019"…Overall meta-analytical results showed significant better healing, recurrence and amputation/revision surgery rates following CS compared to SC. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Using gas-solid mixture conservation laws for volcanic eruptions
منشور في 2013"…Resolutions for this system are presented and compared with other numerical methods demonstrating the fundamental physical and numerical significances to the relative motion within volcanic eruptions.…"
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Sequence conservation and variability of imprinting in the Beckwith–Wiedemann syndrome gene cluster in human and mouse
منشور في 2000"…This first comparative imprinting cluster analysis revealed a high structural and functional conservation of the six orthologous genes identified. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Predictors of inflammatory local recurrence after breast-conserving therapy for breast cancer: matched case-control study
منشور في 2015"…Inflammatory local recurrence(ILR) after breast-conserving surgery for noninflammatorybreast cancer (BC) is associated with dismal prognosis. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Cushion plants act as facilitators for soil microarthropods in high alpine Sweden
منشور في 2022"…D. lapponica cushions on the exposed ridge had significant positive effects on species richness, abundance and diversity index of collembolans, and abundance of oribatids. …"
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Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species
منشور في 2022"…Interestingly, the Arabian Gulf group demonstrated significantly less liking and protection endorsement for animals, including those animals which play an important role in their culture. …"
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Computed tomography-detected hemothorax after blunt chest trauma: Does everyone need an intervention? A retrospective analysis
منشور في 2025"…Most patients (79 %) were successfully managed without tube thoracostomy insertion, while 53 patients (21 %) required tube thoracostomy after failure of conservative management. Patients with larger hemothorax volumes were significantly more likely to require tube thoracostomy (<i>p</i> = 0.001) and had significantly longer hospital stays (<i>p</i> = 0.021). …"
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Comparative Study of the Structural Behaviour of Cast Acrylic & Laminated Glass Under the Impact of Dynamic Loading in Aquatic Applications
منشور في 2023"…The model was adjusted to compare the actual deflection and applied stress criteria with the aforementioned four variable parameters. …"
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
منشور في 2017"…A significant decrease in protein levels of p53 and Bcl-2 and a significant increase in p21 and Bax were observed. …"
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Adaptive Effects of Seeing Green Environment on Psychophysiological Parameters When Walking or Running
منشور في 2019"…Study 2 showed that running in a green environment was associated with an increased level of perceived exertion at similar speeds (compared to other color conditions), while exposure to red induced a significant decrease in the level of tension. …"