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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Econometric Modeling of Gasoline Consumption
منشور في 2008"…Finally, statistical performance measures, such as mean square error, mean average deviation, and mean average percentage error, are presented for all models.…"
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Shear Behavior of One-Way Reinforced Concrete Hollow Slabs Voided with PET Void Formers
منشور في 2023احصل على النص الكامل
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Econometric modeling of electricity consumption in post-war Lebanon
منشور في 2000"…Finally, statistical performance measures such as mean square error, mean average deviation and mean average percentage error are presented for all models.…"
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Site-Adaptation of Modeled Solar Radiation Data: The SiteAdapt Procedure
منشور في 2020"…It was tested at nine sites in a wide range of latitudes and climates, resulting in significant improvements of statistical indicators of dispersion, distribution similarity and overall performance: relative bias is reduced on average from −1.8% and −2.3% to 0.1% and 0.3% for GHI and DNI, respectively; relative root mean square deviation is reduced on average from 17.9% and 34.9% to 14.6% and 29.8% for GHI and DNI, respectively; the distribution similarity is also improved after the site-adaptation (KSI is 3.5 and 3.9 times lower for GHI and DNI at hourly scale, respectively). …"
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Modelling of Asphalt’s Adhesive Behaviour Using Classification and Regression Tree (CART) Analysis
منشور في 2019"…<p>The modification by polymers and nanomaterials can significantly improve different properties of asphalt. …"
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Do commodity price volatilities impact currency misalignments in commodity-exporting countries?
منشور في 2020"…Then, we rely on panel data and a smooth-transition regression model to estimate commodity price volatilities' non-linear impacts on currency misalignments. …"
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A coupled finite element EHL and continuum damage mechanics model for rolling contact fatigue
منشور في 2017"…The results demonstrate that the damage variable has a significant effect on pressure distribution within the contact and depending on the level of damage; the pressure distribution can significantly deviate from the undamaged EHL pressure. …"
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Scatter search for protein structure prediction. (c2008)
منشور في 2008احصل على النص الكامل
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Forecasting Emerging Stock Market Crashes via Machine Learning
منشور في 2023احصل على النص الكامل
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