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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Do Pre-Training and Post-Training Factors Impact IT Training Transfer to the workplace? A Case Study from a Multinational Company in the UAE
منشور في 2016"…The results indicate that pre-training and post-training factors significantly influence IT training transfer to the workplace. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Opportunities for Knowledge Sharing, Knowledge Transfer, and Innovation in the UAE through Academia-Industry Collaboration
منشور في 2013"…Lack of trust, organizational culture, time, intellectual property and confidentiality are found to be important factors that prevent such relationships. On the other hand, financial aspects, knowledge sharing, knowledge transfer, and innovation are among the main elements identified in improving academic-industry collaborations. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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FLACON: A Deep Federated Transfer Learning-Enabled Transient Stability Assessment During Symmetrical and Asymmetrical Grid Faults
منشور في 2024"…The proposed approach effectively incorporates cross-domain deep federated transfer learning (FTL) to leverage local operating data for TSA in a decentralized fashion. …"
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Federated Transfer Learning for Authentication and Privacy Preservation Using Novel Supportive Twin Delayed DDPG (S-TD3) Algorithm for IIoT
منشور في 2021"…As it is considered one of the most open and scalable interacting platforms of information, it successfully helps in the positive transfer of different kinds of data between devices in more significant and local operations of the industry. …"
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The Role of Social Media Influencers in Electric Vehicle Adoption in the UAE
منشور في 2025"…However, source credibility does not significantly moderate the effect of trust on the adoption intention (β = 0.029, p = 0.634). …"
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Preanalytical Stability of CSF Total and Oligomeric Alpha-Synuclein
منشور في 2021"…Interestingly, oligomeric-alpha-synuclein levels remained relatively stable over multiple tube transfers and upon delayed storage.</p><p><br></p><h3>Conclusion</h3><p dir="ltr">Our study showed for the first-time distinct impact of preanalytical factors on the different forms of CSF alpha-synuclein. …"
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
منشور في 2017"…A significant decrease in protein levels of p53 and Bcl-2 and a significant increase in p21 and Bax were observed. …"
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