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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Network Analysis and its Applications in Financial and Digital Assets
منشور في 2025احصل على النص الكامل
doctoralThesis -
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A Comparative study of Technical Efficiency in GCC Islamic Financial Institutions during the Global financial Crisis using Malmquist-Type Data Envelopment analysis
منشور في 2013"…The results suggest that generally GCC and non-GCC IFIs efficiency was not significantly affected by the financial crisis. However, Individual IFIs result showed that some bank has experienced increase or decrease of efficiency after the crisis. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Metaverse and financial markets: A quantile-time-frequency connectedness analysis
منشور في 2024"…The results highlight a significant increase in connectivity during extreme conditions compared to median levels. …"
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Short Term Fluctuations in the CEO Effect: Evidence from the 2008 Financial Crisis
منشور في 2022"…Using mixed effect modeling with crossed and nested factors, we find that the CEO effect significantly drops from the pre-crisis to the crisis period, but increases again to pre-crisis levels in the post-crisis period. …"
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conferenceObject -
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Extent and Mitigation of Financial Toxicity of Immune Checkpoint Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma
منشور في 2025"…Findings suggest that FT significantly limits access to ICIs globally, with heightened impact in resource-limited settings and increasingly recognized in high-income countries as well. …"
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The mediating effect of corporate social responsibility on the relationship between corporate governance and financial performance. (c2016)
منشور في 2016"…Over the years, corporations have concentrated their efforts on increasing the effectiveness of their governance practices. …"
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masterThesis -
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Does the CEO effect differ in times of crisis? Evidence from US and China during the global financial crisis
منشور في 2024"…This study investigates short-term fluctuations in the CEO effect, measured as the proportion of variance in firm performance attributable to individual CEOs, in response to macroeconomic crises, with a specific focus on the global financial crisis. Utilizing multilevel modeling on a 15-year dataset of US firms and assessing three performance metrics, we identify a significant decline (increase) in the CEO effect on accounting-based (market-based) performance measures (measure) from the pre-crisis to the crisis period, followed by a significant rebound post-crisis. …"
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Carbon Performance and Financial Performance: How R&D Makes a Difference Pre‐ and Post‐Paris Accord
منشور في 2024"…Moreover, R&D positively enhances this association, with each additional 1% R&D amplifying the CP's effect on financial performance by 0.154 units. However, following the U.S. withdrawal from the Paris Climate Agreement, the moderating effect of R&D diminishes significantly. …"
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Examining the Shifting Dynamics of the Beveridge Curve in the Turkish Labor Market during Crises
منشور في 2024"…<p dir="ltr">Following the global financial crisis, an increasing amount of attention has been directed towards examining the Beveridge curve (BC), which indicates the relationship between unemployment and vacancy rates. …"