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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Family resources, resilience beliefs, and parental adaptation: A moderated mediation analysis
منشور في 2024"…The present study aims to address this gap by exploring a moderated mediation model that predicts parental stress resulting from the accumulation of pandemic‐related stressors. …"
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The mediating effect of organisational resilience and internal preparedness on the relationship between external vulnerabilities and performance
منشور في 2024"…The relationships between resilient characteristics, resilient capacities, and firm performance were also positive and significant. The mediation results showed an indirect relationship between resilient characteristics and firm performance, and resilient capacities fully mediated this association. …"
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Building Research Capacity in Higher Education: Exploring Confidence as a Mediator of Contextual Support and Research Interest
منشور في 2025"…<p dir="ltr">Building research capacity in higher education depends significantly on understanding the various contextual support systems that influence and shape students' research interests. …"
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The Role of Stakeholder Engagement in Sustainable Business Model Value Creation: The Mediating Effects of Dynamic Capability and Organisational Agility in Dubai’s Private Healthcar...
منشور في 2025"…This study examines the influence of stakeholder engagement on sustainable business model value creation, mediated by dynamic capability and organisational agility. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Key determinants of SMEs’ export performance: a resource-based view and contingency theory approach using potential mediators
منشور في 2020"…These research findings have scientific contribution and significant implications by understanding the effective internal and external export drivers and mediators in an emerging market and enhancing SMEs’ export performance.…"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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The significance of general skills training for early career graduates: relationships with perceived organizational support, job satisfaction and turnover intention
منشور في 2023"…This study also found significant evidence for serial mediation by POS on PGST and its relationship with turnover intention. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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The Mediation Roles of Coping Modalities on the Relationship Between Stress and Quality of Life Among Jordanian Nurses
منشور في 2024"…The results showed that coping significantly mediated the relationship between stress and QOL with variations between PFC and EFC. …"
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Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling
منشور في 2018"…In this work, we investigated the effect of Nox2 loss of function on obesity-mediated alteration of bone remodeling using wild-type (WT) and Nox2-knockout (KO) mice fed with a standard lab chow diet (SD) as a control or a HFD as an obesity model. …"
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The Impact of Leadership Styles on Improving Employee Agility: The Mediating Role of Employee Incentives
منشور في 2024"…Data analyses of this study were conducted through the structural equation modelling technique of SmartPLS. Analyses of the direct relationships suggest that transformational leadership style has a significant impact on employee agility. …"
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Leadership Styles and Faculty Job Satisfaction, Moderators and Mediators, in STEM-related Fields
منشور في 2017"…The influences of moderators and mediators on the relationship between HOD’s leadership styles and faculty job satisfaction are investigated and a new model is developed. …"
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Cytosolic Phospholipase A2-Mediated ICAM-1 Expression Is Calcium Dependent
منشور في 2001"…Cytosolic phospholipase A2 (cPLA2) is a lipid-mediator activated by inflammatory stimuli, which has been shown to mediate ICAM-1 upregulation. …"
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