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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Predicting tendon tissue grafting source from the extensors of long fingers
منشور في 2018"…In addition and from an evolutionary perspective, we hypothesized that the observed significantly higher frequency values of the double-slip and triple-slip types of the EDC of the ring finger, EDC of the little finger, and EDM might indicate a natural selection tendency for a higher independence of the former digits in the future evolution of the human hand.…"
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Can the Salivary Microbiome Predict Cardiovascular Diseases? Lessons Learned From the Qatari Population
منشور في 2021"…</p><h3>Methods</h3><p dir="ltr">Saliva samples from 2,974 Qatar Genome Project (QGP) participants were collected from Qatar Biobank (QBB). …"
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Temporal self-attention for risk prediction from electronic health records using non-stationary kernel approximation
منشور في 2024"…<p dir="ltr">Effective modeling of patient representation from electronic health records (EHRs) is increasingly becoming a vital research topic. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting
منشور في 2025"…Neural networks help address this issue by extracting meaningful patterns from past observations to improve wave height predictions. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Robust and novel attention guided MultiResUnet model for 3D ground reaction force and moment prediction from foot kinematics
منشور في 2023"…Several works have been done on predicting GRF&M from kinematic data captured from the subject’s body with the help of motion capture cameras. …"