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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Prospective study of incidence and predictors of peripheral intravenous catheter-induced complications
منشور في 2014"…Removal time for PIVCs insertion was not a significant predictor of phlebitis (RR =1.46, P=0.08). …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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High School Type as a Predictor of Student Academic Performance and Retention: A Case Study of Student Academic Performance and Retention in relation to High School type qualificat...
منشور في 2016"…The present research attempted to study the relation between student grades in two high school types as a predictor of academic performance in college/university. …"
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Predictors of Mortality in Veno-Arterial Extracorporeal Membrane Oxygenation Regardless of Early Left Ventricular Unloading: A National Experience
منشور في 2025"…Whereas CPR > 20 minutes (aOR 12.45, 95% CI 1.79-86.36; <i>p</i>-value= 0.011) was the only significant positive predictor of mortality with VA-ECMO and IABP. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Consumer Behaviour and Digital Health Innovation: The Case of AI Symptom Checkers
منشور في 2025احصل على النص الكامل
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