The promise of tirzepatide: A narrative review of metabolic benefits حسب Sara Sokary (17337724)

"…Furthermore, limited evidence showed that lost body weight may be primarily due to fat mass reduction. Tirzepatide also significantly decreased food intake, reduced overall appetite scores and increased fasting visual analog scale scores for satiety and fullness across different clinical trials. …"

Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection حسب Atiq ur Rehman (3044409)

"…(v) The effective size of successful agents is reduced recursively while progressing through different states to further facilitate the speed of convergence and decrease the number of features. (vi) The performance comparison with state-of-the-art feature selection methods shows a significant improvement and promise of the proposed method over the existing methods.…"

Chemical characterization and cytotoxic activity evaluation of Lebanese propolis حسب Faour, Wissam H.

"…Toxicity started early after 24 h of incubation and remained till 72 h. Interestingly, the decrease in cell viability was accompanied by a significant increase in p53 protein expression levels and PARP cleavage. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] حسب Abdel Khalek, Maya

"…Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition حسب Sleem, Reem

"…Finally, our results revealed a significant decrease in the ratios of P-ERK/ERK and P-MEK/MEK following treatment. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells حسب Al Sayyed, Fatima

"…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death حسب Tohme, Sara

"…Scavenging ROS using NAC significantly decreases cell death but has minimal effect on autophagy activation, suggesting that the accumulation of ROS is downstream of autophagy activation but upstream of cell death. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy حسب Yahya, Fares

"…The FCN shows a significant decrease in most of the right frontal areas. …"
احصل على النص الكامل

Curcumin encapsulated colloidal amphiphilic block co-polymeric nanocapsules حسب Bechnak, Linda

"…Finally, A375 cells treated with curcumin and the nanocapsules showed a significant increase in single- and/or double-strand DNA breaks upon exposure to light, indicating promising biological effects.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The antioxidant and anticancer effects of Wild Carrot oil extract حسب Shebaby, Wassim Nasri

"…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Effect of Treated Waste-Water on Compaction and Compression of Fine Soil حسب Attom, Mousa

"…The maximum dry unit weight increased for both soils and the optimum water content decreased as much as 13.6% for highly plastic soil. …"
احصل على النص الكامل

Effects of natural organic matter on aggregation kinetics of boron nanoparticles in monovalent and divalent electrolytes حسب Liu, Xuyang

"…The addition of SRHA caused the boron nanoparticles to stabilize and resulted in (1) decreased attachment efficiency for the reaction-controlled regime and (2) an increase in the critical coagulation concentration, in CaCl2 and MgCl2 solutions. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Metformin treatment inhibits motility and invasion of glioblastoma cancer cells حسب Al Hassan, Marwa

"…The results show a significant decrease in the survival of SF268 cancer cells in response to treatment with metformin. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Extraction and characterization of biofunctional lignocellulosic fibers from Pulicaria undulata plant and the effect of alkali treatment on their bio-physicochemical properties حسب Mohammed, Alsafran

"…In contrast, alkali-treated fibers showed a significant decrease in radical scavenging activity (almost 7–8 fold) and reducing power potential (6-fold) and exhibited no antifungal activity, potentially due to the loss of bioactive components such as lignin and essential oils. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Inland Treatment of the Brine Generated from Reverse Osmosis Advanced Membrane Wastewater Treatment Plant Using Epuvalisation System حسب Qurie, Mohannad

"…The increasing of channel number or closed loop time is estimated for enhancing the treatment process and increasing the nutrient uptake. …"
احصل على النص الكامل

Carbon Nanotube Effect on the Ductility, Flexural Strength, and Permeability of Concrete حسب Mohamed O. Mohsen (14590765)

"…Furthermore, the results showed that CNTs would increase the ductility of concrete beams by about 150%. …"

Preparation of albumin-targeted liposomes and the study of their release characteristics using ultrasound حسب Turki, Renad

احصل على النص الكامل

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway حسب Olfa Khalifa (10914452)

"…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …"

Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer حسب Adviti Naik (673163)

"…Following <i>LDHC</i> knockdown, we observed an increase in the secretion of tumor-derived pro-inflammatory cytokines (IFN-γ, GM-CSF, MCP-1, CXCL1), a decrease in the soluble levels of tumor-derived immunosuppressive factors (IL-6, Gal-9) and reduced tumor cell surface PD-L1 expression. …"

Zirconium Silicate/IL/Mxene-based composite membranes for high-temperature fuel cell applications حسب Edwin, Reeves Nayagam

احصل على النص الكامل