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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…By elucidating a mechanistic basis for the increased affinity of the N501Y mutant S1-RBD for ACE2, we believe that the results presented here will aid in developing therapeutic strategies against SARS-CoV-2 including designing of therapeutic agents targeting the ACE2-S1-RBD interaction.…"
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When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial
منشور في 2021"…Univariate analysis showed a significant increase in the frequency of epileptogenic lesions with decreasing age, the presence of developmental delay, and the number and types of seizures at presentation. …"
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Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia
منشور في 2006"…Patient characteristics and results are summarized in Table 1. Only patients 4 and 7 had an increase in Hb of 1.7 and 3 g/dL, respectively, at 6 months. …"
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Psychological inoculation against problematic social media use among adolescents: An experimental study
منشور في 2025"…A mixed ANCOVA was employed to test the intervention's impact on PSMU, post‐intervention attitude changes, and post‐inoculation talk (PIT) about excessive technology use. Results indicated a significant decrease in PSMU levels following active inoculation, particularly in withdrawal, persistence, displacement, and deception symptoms. …"
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Impact of the positive pressure valve on vascular access device occlusions and bloodstream infections
منشور في 2009"…Potential benefits of using PPVs on VADs include decreased VAD-related complications, improved patient outcomes, and cost savings. …"
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Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain
منشور في 2018"…</p><p dir="ltr"><br></p><h3>Results</h3><p dir="ltr">The FTIR results revealed that in the lesioned gray matter the relative distribution of lipid, lipid acyl and protein contents decreased significantly. …"
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The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
منشور في 2018"…These mega-projects may include the construction of major buildings, roads, railway lines and airports. …"
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Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review
منشور في 2022"…Regarding the vertical jaw relation, one study reported a significant decrease in mandibular plane inclination in OC and a significant increase in OOS. …"
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Formation of Trihalomethanes during Seawater Chlorination
منشور في 2010"…Chlorination of seawater has shown significant increase in total THMs (TTHMs) and in bromoform concentrations. …"
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Investigation of positive education implementation and its impact on students' wellbeing and academic self-efficacy in K-12 private schools in Dubai
منشور في 2022"…The findings revealed the following: 1) in recent years there has been increasing positive education implementation grounding in the recent international, national, local, and educational authority policies and initiatives. 2) absence of standardised local and school policy related to positive education implementation has led to the need for adaptability of positive education implementation across school. 3) there has been strong engagement of the internal school community (teachers, school leaders and students) with external school community (parents). 4) significant changes in the overall level DSWC indicators associated with social emotional wellbeing, life satisfaction, perseverance, feeling safe, and belonging to school. 5) insignificant changes associated with DSWC indicators associated with emotional regulation, happiness, optimism, academic self-concept, cognitive engagement, engagement (flow), peer belonging and school climate. 6) PASS assessment factors show increase in wellbeing, motivation and self-efficacy for regulation and decrease in academic self-efficacy. 7) significant increase in emotional, social wellbeing and academic self-efficacy among students due to positive education implementation as perceived by teachers, parents, and students.…"
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Vocal Changes in Patients With Polycystic Ovary Syndrome
منشور في 2011"…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …"
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Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy
منشور في 2024"…The FCN shows a significant decrease in most of the right frontal areas. …"
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Application of hierarchical oligonucleotide primer extension (HOPE) to assess relative abundances of ammonia- and nitrite-oxidizing bacteria
منشور في 2017"…There was a corresponding significant decrease in the relative abundance of NOB, specifically Nitrospira and those affiliated to comammox, during the shock loading. …"
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