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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry
منشور في 2025احصل على النص الكامل
doctoralThesis -
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Diversity of protists in dryland habitats of Qatar revealed by environmental metabarcoding
منشور في 2025"…This approach enabled detection of diverse eukaryotic lineages and facilitated assessment of their diversity and relative abundance. Protist diversity differed significantly between habitats and among samples, while richness varied significantly between habitats. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Enhancing Arabic Reading Proficiency as a Second Language: Unveiling the Significance of Audiobooks for Middle School Students
منشور في 2024"…Eleven Arabic teachers from different Dubai schools participated in this qualitative study to determine the significance of audiobooks for non-native Arabic speakers enrolled in Dubai middle schools. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Hedging Strategies Using Financial Derivatives in Different Industries
منشور في 2025احصل على النص الكامل
doctoralThesis -
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Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation
منشور في 2022"…A mitohormetic type of relationship was observed with HRV features increasing and then decreasing with increasing HN concentration. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Revealing Size‐Dependency of Ionic Liquid to Assist Perovskite Film Formation Mechanism for Efficient and Durable Perovskite Solar Cells
منشور في 2023"…Theoretical calculations in conjunction with experimental measurements revealed that small-sized anion can more effectively reduce defect density by filling halide vacancies within perovskite bulk materials, resulting in suppression of charge-carrier recombination, an extended photoluminescence lifetime, and significantly improved device performance. …"
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Comparative Analysis of Engagement and Academic Self‐Concept among Nursing Students: Differences in Study Modalities
منشور في 2024"…Correlational analysis within each modality revealed significant relationships among the subdomains of USEI and ASCQ.…"
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Understanding dispute resolution in the Middle East region from perspectives of different stakeholders
منشور في 2016"…However, this growth is accompanied by an inevitable increase in claims and disputes, which consequently leads to significant delays and additional costs to the project. …"
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