يعرض 1 - 20 نتائج من 491 نتيجة بحث عن '(( significant increase decrease ) OR ( significantly ((complex pathways) OR (complex patterns)) ))', وقت الاستعلام: 0.12s تنقيح النتائج
  1. 1

    Detection of statistically significant network changes in complex biological networks حسب Raghvendra Mall (581171)

    منشور في 2017
    "…<h3>Background</h3><p dir="ltr">Biological networks contribute effectively to unveil the complex structure of molecular interactions and to discover driver genes especially in cancer context. …"
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

    منشور في 2019
    "…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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    A photoactivatable chemotherapeutic Ru(II) complex bearing bathocuproine ligand efficiently induces cell death in human malignant melanoma cells through a multi-mechanistic pathway حسب Elias, Maria George

    منشور في 2021
    "…Photoactivated chemotherapy (PACT) is an emerging strategy for targeted cancer therapy. Strained Ru complexes with pseudo-octahedral geometry may undergo photo-induced ligand dissociation, forming aquated photoproducts that are significantly more cytotoxic compared to the precursor complex. …"
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    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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    Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting حسب Aryan Bhambu (18767731)

    منشور في 2025
    "…Stacked hidden layers are incorporated to facilitate deep representation learning, allowing the extraction of complex patterns from the data. Forecasts are generated by integrating the outputs of each layer using an ensemble approach. …"
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

    منشور في 2014
    "…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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    Evolutionary algorithms for state justification in sequential automatic test pattern generation حسب El-Maleh, Aiman H.

    منشور في 2005
    "…Sequential circuit test generation using deterministic, fault-oriented algorithms is highly complex and time consuming. New approaches are needed to enhance the existing techniques, both to reduce execution time and improve fault coverage. …"
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    Blue collar laborers’ travel pattern recognition: Machine learning classifier approach حسب Aya Hasan Alkhereibi (17151070)

    منشور في 2021
    "…Furthermore, whilst the Bagged Clusters and Pamk Clusters techniques on the three attributes yielded similar results, the Cmeans Clusters differed significantly in a number of the clusters. Applying such pattern recognition models on big and complex activity datasets could assist transport planners to understand the travel needs of segments of the population well and formulating better-informed strategies.…"
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    Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells حسب Shebaby, Wassim N.

    منشور في 2014
    "…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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    Integrating Genome Sequencing and Untargeted Metabolomics in Monozygotic Twins with a Rare Complex Neurological Disorder حسب Rulan Shaath (17112852)

    منشور في 2024
    "…The significant metabolites belong to essential pathways such as lipids and amino acid metabolism. …"
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    EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis حسب Yahya, Fares

    منشور في 2020
    "…Behaviorally, all subjects demonstrated vigilance decrement as reflected by the significant increase in response time and reduced accuracy. …"
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