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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Examining the Deviation in Energy Saving Estimations Due to the Use of the Degree Days Method
منشور في 2022"…The Degree Days can be calculated with a variety of base temperatures resulting in different values. …"
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Performance Prediction Using Classification
منشور في 2019"…The objective of this study is to determine the best classification models for predicting At Risk status of students in their first semester of an undergraduate degree program. A comprehensive evaluation requires that multiple models with different algorithms were analyzed using key performance measures. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Multilayer Reversible Data Hiding Based on the Difference Expansion Method Using Multilevel Thresholding of Host Images Based on the Slime Mould Algorithm
منشور في 2022"…As a result, the embedding capacity in each class can increase by reducing the value of the difference between two consecutive pixels, and the distortion of the marked image can decrease after inserting the personal data using the DE method. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Do research experience programs promote capacity building in Qatar: Investigating the trend and participation differences
منشور في 2023"…Also, statistically significant differences were found in student participation rates among students' gender and ethnic distributions. …"
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Investigation of implementing STEM projects in a selective school in the United Arab Emirates
منشور في 2017"…STEM projects are pedagogies that suit students with different abilities. The results show a significant difference in attitudes between males and females toward STEM projects and STEM careers.…"
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Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta...
منشور في 2023"…<p dir="ltr">The frequency and severity of climate change are projected to increase, leading to more disasters, increased built environment system (BES) vulnerability, and decreased coping capacity. …"
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A Cross-cultural study of pragmatically requestive speech act realization patterns
منشور في 2014"…It also looks at the types of politeness strategies, which could increase or decrease the degree of the imposion on the hearer(s), employed by the two groups in terms of the aforementioned sociolinguistic variables. …"
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Implementation of corporate governance rules and procedures in lebanese firms
منشور في 2014"…This study aims to evaluate the degree of disclosure implementation of corporate governance rules in developing/emerging nations by studying the Lebanese case. …"
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
منشور في 2017"…A significant decrease in protein levels of p53 and Bcl-2 and a significant increase in p21 and Bax were observed. …"
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
منشور في 2018"…The cases simulated were 12 different PV setups which included 6 different PV technologies on a 5 and 25 degree tilt: 1. …"
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