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Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis
منشور في 2002"…BACKGROUND The specific activity of the non-receptor protein tyrosine kinase, Src, is increased in the majority of colon and rectal adenocarcinomas compared to normal mucosa. …"
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Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas...
منشور في 2023"…Following cell entry, LF cleaves all mitogen- activated protein kinase kinase (MEKs) leading to the inactivation of the MAPK pathway. …"
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masterThesis -
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The Effect of Recombinant Anthrax Lethal Toxin on Breast Cancer Cell Motility, Adhesion, and Invasion
منشور في 2020"…Additionally, cells treated with LT showed an increase in adhesion, decrease in invasion across a collagen matrix, and in increase in Rho A activation. …"
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masterThesis -
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Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia
منشور في 2023"…At the histological level, we found that GSK429286 significantly increased the size of new microvessels in the regenerating areas of ischemic muscles compared with vehicle-treated ones. …"
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The Safety of Novel Therapies in Chronic Lymphocytic Leukemia in the Era of Intermittent Fasting: A Pharmacology-Based Review
منشور في 2024"…Concurrently, novel agents (NAs) like venetoclax and Bruton tyrosine kinase inhibitors (BTKIs) have revolutionized the treatment of chronic lymphocytic leukemia (CLL). …"
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Effect of Crude Oil Products on the Geotechnical Properties of Sandy Soil
منشور في 2011احصل على النص الكامل
doctoralThesis -
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Phospholipase C negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells
منشور في 2007"…Inhibition of protein kinase C using bisindolylmaleimide mimics the effect of PLCc inhibition on Rac activation, but not on Cdc42 activation. …"
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The efficacy of transcranial direct current stimulation in patients with medication overuse headaches secondary to chronic migraines (P4.128)
منشور في 2018"…There was also a significant decrease in the consumption of analgesic medications in the DLPFC group and in the pain intensity in the Occipital group. …"
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Bond durability of sand coated and ribbed basalt FRP bars embedded in high-strength concrete
منشور في 2023"…Ribbed bars had significantly higher bond strength than sand-coated bars and were less affected by the surrounding environments. …"
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A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein
منشور في 2016"…Interestingly, no increase in phosphorylation was observed when PLK2 and h-asyn were co-expressed in rat striatal neurons. …"
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The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France
منشور في 2018"…Given that equity financing becomes less costly, we find that the propensity to issue new SEOs increases among high-divergence firms after IFRS adoption. …"
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An Exploration of Smoking Patterns Among People with Serious Mental Illness Attending an Outpatient Clinic in Qatar
منشور في 2022"…Many countries worldwide have observed a decrease in the prevalence of tobacco smoking; however, the smoking rates among people with SMI have declined much less than in those without mental illness. …"
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Estimation of Virtual Trust on Driverless Cars using Type-1 Fuzzy logic
منشور في 2024"…These vehicles boost confidence, increase road capacity, and decrease traffic accident. The major benefit is a decrease in traffic enforcement, plus self-driving cars consume less fuel than other types of vehicles and don't require auto insurance. …"
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Accelerating Care: Enhancing Patient Satisfaction through a Quality Initiative in the Obstetrics and Gynaecology Emergency Department at Al Wakra Hospital, Qatar
منشور في 2023"…The proportion of patients spending less than 8 hours in the OB ED observation beds rose from 74% in January 2022 to over 98% in 2023. …"
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Stemming cardiovascular diseases in Qatar
منشور في 2015"…Many of the heart attack and stroke patients had diabetes, hypertension, high cholesterol, and/or were smokers, whereas controls were much less likely to have these factors.</p><p>All of these factors are associated with reduced physical activity and increased consumption of high-fat foods. …"
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Multilayer Reversible Data Hiding Based on the Difference Expansion Method Using Multilevel Thresholding of Host Images Based on the Slime Mould Algorithm
منشور في 2022"…In the DE-based RDH method, finding spaces that create less distortion in the marked image is a significant challenge, and has a high insertion capacity. …"
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