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Effect of partial medial meniscectomy on anterior tibial translation in stable knees
منشور في 2013"…Our values might reflect a temporarily increase of anterior laxity under specific conditions but whether a significant laxity remains in some knees, such changes may lead to higher cartilage loading and early osteoarthritis.…"
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Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study
منشور في 2023"…<h3>Purpose</h3><p dir="ltr">The use of suction drains in total knee arthroplasty (TKA) remains controversial. The aim of this study is to compare the outcomes of patients who received suction drains versus those who did not, focusing on blood loss, blood transfusion need, and length of hospital stay.…"
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Knee Angle Affects Posterior Chain Muscle Activation During an Isometric Test Used in Soccer Players
منشور في 2019"…Conclusions: These results indicate that biceps femoris and overall posterior chain muscle activation is increased with the knee positioned at 30° of flexion; however, the 90° angle displayed less variation in performance within individual participants, especially in the gluteus maximus and medial gastrocnemius. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care
منشور في 2025"…Low-molecular-weight heparin (LMWH) is recommended for VTE prophylaxis (VTEp). We investigated whether switching from fixed-dose dalteparin to anti-Xa-guided enoxaparin prophylaxis reduces VTE without increasing the risk of bleeding among hospitalized trauma patients.…"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
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The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France
منشور في 2018"…Accordingly, we find that, following IFRS adoption, earnings management activities decrease among high-divergence firms prior to issuing SEOs. …"
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The efficacy of transcranial direct current stimulation in patients with medication overuse headaches secondary to chronic migraines (P4.128)
منشور في 2018"…There was also a significant decrease in the consumption of analgesic medications in the DLPFC group and in the pain intensity in the Occipital group. …"
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Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank
منشور في 2025"…However, BMD measures significantly contributed to predicting stiffness after controlling for sociodemographic variables (R2 = 0.065, ΔF(7, 1724) = 3.34, p = 0.002), with a higher total body BMD associated with increased stiffness and a higher trunk BMD associated with decreased stiffness. …"
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Rescue cerclage
منشور في 2006"…Women who required rescue cerclage after failed prophylactic cerclage (n = 12) were 50% less likely to reach 28 weeks. Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. …"
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