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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
منشور في 2021"…Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …"
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masterThesis -
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation
منشور في 2025"…In this study, we demonstrate that Prist effectively inhibits the proliferation of T-ALL cell lines (Jurkat and Molt 4) by inducing G0/G1 cell cycle arrest and triggering intrinsic and extrinsic caspase-dependent apoptosis. Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"
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Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia
منشور في 2019"…<p dir="ltr">Acute lymphoblastic leukemia (ALL) is a significant cancer of children resulting from the clonal proliferation of lymphoid precursors with arrested maturation. …"
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Methane production enhancement from Tetraselmis biomass co-digestion using frying oil residue as co-substrate and ultrasonication as pretreatment
منشور في 2023"…Tetraselmis sp. microalgae biomass co-digestion with frying oil residue was investigated without or with an ultrasonication pretreatment to enhance methane production. …"
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Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (<em>Danio rerio</em>)
منشور في 2020"…Mechanistically, we further showed that resveratrol inhibits ROS increase, prevents mitochondrial membrane potential dysfunction, and counteracts cell apoptosis/necrosis elicited by ZnO NP. …"
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Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
منشور في 2021"…In addition, we established the antitumor effects of SNG through reactive oxygen species (ROS) production, as inhibiting ROS production prevented the apoptosis-inducing potential of SNG. …"
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The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
منشور في 2020"…In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. …"
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masterThesis -
10
Influence of co-current vapor flow on falling film over horizontal tube
منشور في 2021"…As a result, part of seawater evaporates and vapor is generated. Vapor flows in either co-current direction, cross direction or combination of both. …"
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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis
منشور في 2020"…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations.…"
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Upgrading co-pyrolysis products from ternary biomass: An investigative study of commercial and locally-made catalysts
منشور في 2024"…<p dir="ltr">Catalysts play a pivotal role in influencing product yields and compositions in pyrolysis processes, offering significant advantages for biomass conversion. This study investigates the impact of natural and commercial catalysts on the co-pyrolysis of ternary biomass at two different temperatures (550 °C and 750 °C). …"
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Theoretical insight into effect of cation–anion pairs on CO<sub>2</sub> reduction on bismuth electrocatalysts
منشور في 2020"…<p dir="ltr">This study presents theoretical insight into the mechanism of the CO<sub>2</sub> reduction reaction (CO<sub>2</sub>RR) to formic acid (HCOOH) on Bi (0 1 2) surfaces in the presence of alkali metal cations (M<sup>+</sup>: Cs<sup>+</sup>, K<sup>+</sup>, and Li<sup>+</sup>) and/or halide anions (X<sup>−</sup>: Cl<sup>−</sup>, Br<sup>−</sup>, and I<sup>−</sup>) using density functional theory (DFT). …"
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Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent
منشور في 2019"…Ovarian cancer cell lines were negative for annexinV staining while showing loss of membrane integrity and absence of caspase activation, indicating caspase-independent, non-apoptotic cell death. [HuArgI (Co)-PEG5000]-induced arginine deprivation led to extensive and prolonged activation of autophagy, which proved to be deleterious to cell survival since its inhibition led to a significant decrease in cytotoxicity. …"
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article -
15
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
منشور في 2024"…We also found that BTZ exerted its antitumor effects by generating reactive oxygen species (ROS), as blocking ROS production significantly reduced BTZ-induced apoptotic cell death. …"
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Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H<sub>2</sub>S: DFT study
منشور في 2021"…Particularly, the response of H<sub>2</sub>S to Cu/Zn-ZGNR system demonstrated a significant high value of 48.92%. Therefore, the newly developed co-doped Cu/Zn-ZGNR based gas sensor can be recommended as a highly sensitive H<sub>2</sub>S</p><h2>Other Information</h2><p dir="ltr">Published in: Superlattices and Microstructures<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.spmi.2021.106900" target="_blank">https://dx.doi.org/10.1016/j.spmi.2021.106900</a></p>…"
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Advanced direct air capture of CO<sub>2</sub> using air conditioning systems: a life cycle assessment
منشور في 2025"…For the capture of 1 kg of CO<sub>2</sub>, the DAC-HVAC system results in 0.206 kg CO<sub>2</sub> eq. …"
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Thermo-economic analysis of a novel P2X polygeneration system for hydrogen, ammonia, and methanol production with near-zero emissions
منشور في 2025"…The system's levelized cost of hydrogen (LCOH) decreases significantly from $1.70/kg to $0.80/kg, and the levelized cost of electricity (LCOE) decreases from 4.30 ¢/kWh to 3.30 ¢/kWh. …"
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