The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"

Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation حسب Zreik, Tony

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Significance of microscopically incomplete resection margin after esophagectomy for esophageal cancer حسب Markar, Sheraz R.

"…There were significant differences between the groups in postoperative histology, with an increase in pathological stage III and TRG 4–5 in the R1 group. …"
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Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy حسب Hamed Elgendy (14148846)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"

Active distribution network type identification method of high proportion new energy power system based on source-load matching حسب Qinlin, Shi

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Accessibility of large events: an empirical study of the Expo 2020 Dubai حسب María Jiménez-Andres (19170913)

"…The objective of this paper is to contribute to understanding the accessibility of large events in an increasingly technology-dependent industry. …"

Reduced graphene aerogels as energy efficient selective oil sorbents حسب Junaid Saleem (14670322)

"…The presence of H₂ significantly decreased the oxygen-containing functional groups in graphene aerogel. …"

Self-reported awareness and attitude of cancer patients towards clinical nurse coordinators حسب Deeb, Ahmad

"…Methods: This is a cross sectional study that was conducted by distributing a self-reported and anonymous survey to 240 cancer patients visiting the center. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems حسب Raka Jovanovic (17947838)

"…The results also show that high speed chargers have a more significant impact than an increase in battery sizes of the EBs.…"

Autism spectrum disorder in Qatar: Profiles and correlates of a large clinical sample حسب Fouad Alshaban (6176771)

Aerosol Optical Thickness over Large Urban Environments of the Arabian Peninsula—Speciation, Variability, and Distributions حسب Dillan Raymond Roshan (18094867)

"…Over the past decade, the mean annual aerosol optical thickness (AOT) values were in the range of 0.3–0.5, which is attributed to both mineral dust (60–70%) and anthropogenic activities (20–30%). An increase in AOT values between 2005 and 2009 is attributed to increased dust generation from the Sahel region in Northern Africa, and the Fertile Crescent (Syria, Iraq, Jordan) due to an extended dry period. …"

Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients حسب Asmaa Al-mansouri (16931739)

"…<h3>Background</h3><p dir="ltr">The management of chronic kidney disease (CKD) and its complications places a significant burden on patients, resulting in impairment of their health-related quality of life (HR-QOL). …"

Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model حسب Halema Al-Kandari (6316961)

"…However, both nanocomposites should be used with caution at concentration higher than the NOEC (400 mg/L), in particular RGOTi, which significantly (i) caused pericardial and yolk sac edema; (ii) decreased the hatching rate, locomotion, and hematopoietic activities; and (iii) affected the heart rate. …"

Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy حسب Palavecino, Martin

"…Although transfusion rates can be reduced to almost 0 in uncomplicated hepatectomies, the blood transfusion rates associated with liver resection remain significant at tertiary referral centers, such as ours. …"
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Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice حسب Ann Van der Jeugd (18629695)

"…Chronic sodium selenate treatment efficiently reversed hippocampal-dependent learning and memory impairments, and behavior- and neuropsychiatric-like symptoms in old female 3xTg-AD mice. Selenium significantly decreased the number of aggregated tau-positive neurons and astrogliosis, without globally affecting amyloid plaques, in the hippocampus of 3xTg-AD mice. …"

An imageable retinoid acid derivative to detect human cancer xenografts and study therapeutic dosing to reduce its toxicity حسب Wang, Wei

"…In addition, retinoic acid can reverse premalignancy, significantly decrease second primary tumors and provide a treatment benefit in head and neck, lung, esophagus, colon and bladder cancer. …"
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Ethnic-specific association of amylase gene copy number with adiposity traits in a large Middle Eastern biobank حسب Niccolo’ Rossi (14152692)

"…Indeed, lower AMY1 CN was associated with increased total and trunk fat percentages in Arabs (P < 4.60 × 10−3) but not in Persians. …"