Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros حسب Mesmar, J.

"…In addition, ZNE significantly decreased the migratory and invasive capacity of Capan-2 with a concomitant downregulation of integrin α2 and increased cell–cell aggregation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening حسب Shurbaji, Samar Haroon

احصل على النص الكامل
احصل على النص الكامل

Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening. حسب Shurbaji, Samar

احصل على النص الكامل
احصل على النص الكامل

NADPH-derived ROS generation drives fibrosis and endothelial-to-mesenchymal transition in systemic sclerosis: Potential cross talk with circulating miRNAs حسب Posadino, Anna Maria

"…Sera from SSc patients showed significant changes in the expression of a set of fibrosis/EndMT-associated microRNAs (miRNA), including miR-21, miR-92a, miR-24, miR-27b, miR-125b, miR-29c, and miR-181b, which resulted significantly upregulated as compared to healthy donors sera. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia حسب Kuttikrishnan S.

"…Sang mediates its anti-cancer activity by generation of reactive oxygen species (ROS) due to depletion of glutathione level in leukemic cell lines. …"
احصل على النص الكامل
احصل على النص الكامل

Signaling pathways activated by PACAP in MCF-7 breast cancer cells حسب Zibara, Kazem

"…Furthermore, PACAP induced ROS through H₂O₂ production whereas pretreatment with NAC inhibitor decreased AKT and ERK phosphorylation, but not p38. …"
احصل على النص الكامل
احصل على النص الكامل

Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties حسب Mesmar, Joelle

"…Non-cytotoxic concentrations of OSEE attenuated cell proliferation and induced G0/G1 cell cycle arrest, which was associated with phosphorylation of p38 MAPK, an increase in the levels of tumor suppressor protein p21, and a decrease of proliferation marker protein Ki67. Additionally, only higher concentrations of OSEE were able to attenuate inhibition of proliferation induced by the ROS scavenger N-acetyl cysteine (NAC), indicating that the anti-proliferative effects of OSEE could be ROS-dependent. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

ASSOCIATION BETWEEN INSULIN RESISTANCE AND NITRIC OXIDE IN HUMAN RETINAL MICROVASCULAR ENDOTHELIAL CELLS IN VITRO حسب Bushra, Sumbul

"…This study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably reduced with insulin treatment after 1hour, 2 hours and 4 hours. …"
احصل على النص الكامل

Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro حسب Rizk, Nasser Moustafa

"…This study demonstrated that hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis. eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours. …"
احصل على النص الكامل
احصل على النص الكامل

Individual and Synergic Effects of Phosphorus and Gibberellic Acid on Organic Acids Exudation Pattern, Ultra-Structure of Chloroplast and Stress Response Gene Expression in Cu-Stre... حسب Alatawi, Aishah

"…Results revealed that C. capsularis tolerated up to 200 mg kg−1 Cu concentration without a significant (P < 0.05) decrease in biomass, plant height and root length but further increase in Cu concentration from 400 mg kg−1 exhibited a significant reduction in plant height, root length, stem fresh weight, stem dry weight, plant fresh weight and plant dry weight. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes حسب Younes, Noura B.

"…In addition, DHA-treatment of hypoxic cells caused a significant reduction in the apoptosis rate and ROS production with decreased lipid peroxidation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Phase change materials for thermal energy storage applications in greenhouses: A review حسب Nishad S.

"…Greenhouses represent one of the largest energy-demanding sectors, requiring energy for indoor environment control for plant growth and crop yield. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes حسب Younes, Noura B.

"…Results: Under hypoxia conditions, DHA treatment resulted in significant changes in all critical parameters of adipocyte biology including HIF-1α RNA expression (decreased by 50%), decreased lactate and glycerol release (66% and 25% respectively), and reactive oxygen species (ROS) production (decreased by 15%), while glucose uptake was decreased by 25% accompnied by decreased secretion of pro-inflammatory markers (Interleukin 6 IL-6, 31% reduction) , macrophage chemoattractant protein 1 MCP-1 (38% reduction) and leptin (14% reduction), and increased adiponectin secretion (by 45%). …"
احصل على النص الكامل

Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation حسب Feng, Samuel

"…Mitochondrial ATP production is the main source of reactive oxygen species (ROS) and hence the regulation of ROS becomes an important issue in maintaining optimal ANS functionality. …"
احصل على النص الكامل
احصل على النص الكامل

Changing Trends in the Referral and Timing of Treatment for Congenital Cryptorchidism: A Single-Center Experience from Bosnia and Herzegovina. حسب Zvizdic, Zlatan

"…The analysis of the observed two periods (2008-2010 and 2015-2017) showed a statistically significant decrease in the mean referral age and the mean age at surgery over the last 5 years (2015-2017) (p = 0.007 and p = 0.003, respectively). …"
احصل على النص الكامل
احصل على النص الكامل

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase حسب Othman, Amira

"…Treatment of diabetic mice with baicalein significantly decreased retinal HETE, ICAM-1, VCAM-1, IL-6, ROS generation, and NOX2 expression. …"
احصل على النص الكامل
احصل على النص الكامل

Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells حسب Posadino, Anna Maria

"…Treatment of PC3 cells with 30 and 100μg/ml PE significantly decreased cell viability and proliferation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Determination of the main factors contributing to increases in medicine expenditures for the National Health Insurance Fund in Sudan حسب Mousnad, M.A.

"…Relative prices increased by 6.73%; Quantity increased by 91.04%, and the residual contribution decreased by 18.44%. Conclusion: Price factors, quantity and residual are significant determinants of expenditure for the National Health Insurance Fund in Sudan. …"
احصل على النص الكامل

Factors Affecting Waterpipe Tobacco Smoking among University Students in Qatar. حسب Al-Jayyousi, Ghadir Fakhri

"…Participants were selected through stratified random sampling of students in the largest national university in Qatar. Data were collected anonymously using an online questionnaire. …"
احصل على النص الكامل
احصل على النص الكامل

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis... حسب Anwar-Mohamed, Anwar

"…The induction of CYP1A1 by these metabolites seems to be ligand-independent, possibly through a decrease in HSP90 protein expression levels. The metabolites also increased ROS production, which was significantly higher than that produced by As(III). …"
احصل على النص الكامل
احصل على النص الكامل