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Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
منشور في 2021"…HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. …"
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Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer
منشور في 2025"…BackgroundHER2-positive breast cancer (BC) is highly aggressive with a poor prognosis. …"
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HER2-positive apocrine carcinoma of the breast: a population-based analysis of treatment and outcome
منشور في 2022"…HER2+/APO tumors tend to have a less aggressive phenotype and a more favorable outcome despite a markedly lower ER/PR positivity.</p><h2>Other Information</h2> <p> Published in: Breast Cancer Research and Treatment<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s10549-022-06578-4" target="_blank">http://dx.doi.org/10.1007/s10549-022-06578-4</a></p>…"
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Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positiv...
منشور في 2009"…The status of the axillary lymph nodes in nonmetastatic lymph node-positive breast cancer (BC) patients remains the single most important determinant of overall survival (OS). …"
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Gene Expression and miRNAs Profiling: Function and Regulation in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
منشور في 2019"…Despite the anti-HER2 and cytotoxic chemotherapy, HER2 subtype is an aggressive disease with significant mortality. Recent advances in molecular biology techniques, including gene expression profiling, proteomics, and microRNA analysis, have been extensively used to explore the underlying mechanisms behind human breast carcinogenesis and metastasis including HER2-positive breast cancer, paving the way for developing new targeted therapies. …"
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Targeting HER2-positive breast cancer cells by a combination of dasatinib and BMS-202: Insight into the molecular pathways
منشور في 2024"…</p><h3>Conclusion</h3><p dir="ltr">Our findings implicate that a combination of DA and BMS-202 could have a significant impact on the management of HER2-positive breast cancer.…"
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Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
منشور في 2021"…<p>HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. …"
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Breast cancer screening in Lebanon: Understanding knowledge, attitudes and barriers
منشور في 2024"…Background Breast cancer (BC) has been increasing in both prevalence and incidence in Lebanon. …"
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Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
منشور في 2023احصل على النص الكامل
doctoralThesis -
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Discrimination of breast cancer from benign tumours using Raman spectroscopy
منشور في 2019"…Breast cancer is diagnosed by histopathological examination of breast biopsy material but this is subjective and relies on morphological changes in the tissue. …"
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Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
منشور في 2018احصل على النص الكامل
doctoralThesis -
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Mixed precision iterative refinement with adaptive precision sparse approximate inverse preconditioning
منشور في 2025"…<p dir="ltr">Hardware trends have motivated the development of mixed precision algorithms in numerical linear algebra, which aim to decrease runtime while maintaining acceptable accuracy. …"
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Correction: Discrimination of breast cancer from benign tumours using Raman spectroscopy
منشور في 2019"…<p dir="ltr">Correction to: Discrimination of breast cancer from benign tumours using Raman spectroscopy. …"
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Diagnostic test accuracy of AI-assisted mammography for breast imaging: a narrative review
منشور في 2025"…The motivation for this research lies in addressing the need for enhanced diagnostic tools in breast cancer screening, where early detection can significantly impact patient outcomes. …"
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
منشور في 2020"…In conclusion, sumac demonstrated significant oncostatic activities in rodent models of breast carcinoma that were validated by mechanistic studies in vivo and in vitro.…"
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Imaging Patterns in Breast Cancer for Women Under 40 Years: A Descriptive Cohort Study
منشور في 2024"…Out of the 73 patients who underwent genetic tests, 32.9% tested positive for gene mutations. No statistically significant correlation was found between specific age groups and breast composition (<i>P</i> = 0.216), specific mammogram abnormalities such as masses (<i>P</i> = 0.262), or microcalcifications (<i>P</i>= 0.421). …"
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Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer
منشور في 2015"…The expression pattern of the most significant MRs was then evaluated by immunohistochemistry (IHC) in two independent cohorts of IBCs (n = 39) and nIBCs (n = 82) and normal breast tissues (n = 15) spotted on tissue microarrays. …"
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CXCR7 signaling promotes breast cancer survival in response to mesenchymal stromal stem cell-derived factors
منشور في 2022"…Interestingly, significant positive correlation between CXCR7 and CXCL12 gene expression (Pearson = 0.3, p = 2.0 × 10–16) was observed in breast cancer patients, suggesting a biological role for the CXCR7/CXCL12 genetic circuit in breast cancer biology. …"
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Breast Cancer Screening Practices in a Tertiary Care Center in the State of Qatar: A Cross-Sectional Survey
منشور في 2021"…While the attitude towards breast cancer screening is positive, the overall compliance with the national recommendations is sub-optimal. …"