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Acoustic radiation-free surface phononic crystal resonator for in-liquid low-noise gravimetric detection
منشور في 2021"…This energy confinement results in a significant quality factor improvement and reduces frequency noise. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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An End-to-End Deep Learning Framework for Real-Time Denoising of Heart Sounds for Cardiac Disease Detection in Unseen Noise
منشور في 2023"…The results presented in the paper indicate that our proposed architecture demonstrated a robust denoising performance on different datasets with diverse levels and characteristics of noise. The proposed deep learning-based PCG denoising approach is a pioneering study that can significantly improve the accuracy of computer-aided auscultation systems for detecting cardiac diseases in noisy, low-resource hospitals and underserved communities. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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Optimisation of exhaust emissions, vibration, and noise of unmodified diesel engine fuelled with canola biodiesel-diesel blends with natural gas addition by using response surface...
منشور في 2024"…<p dir="ltr">The paper presents methods to determine the optimum input parameters of CNG addition, biodiesel blend ratio, and engine speed to improve engine responses in terms of exhaust emissions, vibration, and noise of CNG-biodiesel-diesel fuelled engines. Box–Behnken based on response surface methodology was used to predict and optimise input parameters. …"
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Incorporation of Robust Sliding Mode Control and Adaptive Multi-Layer Neural Network-Based Observer for Unmanned Aerial Vehicles
منشور في 2024"…<p dir="ltr">The control and state estimation of Unmanned Aerial Vehicles (UAVs) provide significant challenges due to their complex and nonlinear dynamics, as well as uncertainties arising from factors such as sensor noise, wind gusts, and parameter fluctuations. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Learning-Based Automatic Modulation Classification
منشور في 2015احصل على النص الكامل
doctoralThesis