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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"
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Effect of increasing the number of anchors on the flexural performance of FRP-strengthened RC beams
منشور في 2024"…Results showed that increasing the number of anchors significantly improved the flexural behavior of the strengthened beam in terms of the beam's response at failure and the strain utilized in the FRP laminates. …"
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Influence of Household Water Filters on Bacteria Growth and Trace Metals in Tap Water of Doha, Qatar
منشور في 2018"…<p>Deteriorating water quality from aging infrastructure, growing threat of pollution from industrialization and urbanization, and increasing awareness about waterborne diseases are among the factors driving the surge in worldwide use of point-of-entry (POE) and point-of-use (POU) filters. …"
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
منشور في 2006احصل على النص الكامل
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
منشور في 2025"…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…"
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Assessing the eco-environmental aspects of fossil fuels-based units substitution of Point Aconi thermal power plant by green-based energies: a case study of Canada
منشور في 2024"…<p dir="ltr">Canada possesses significant potential in harnessing renewable energy from its vast and diverse geography, which can generate clean electricity. …"
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Implementing CYP2C19 Pharmacogenetic Testing for Personalized Antiplatelet Therapy: Findings From the QPGx-CARES Initiative
منشور في 2025"…<h3 dir="ltr">Purpose</h3><p dir="ltr">CYP2C19 loss-of-function (LoF) alleles are associated with increased cardiovascular risk in clopidogrel-treated percutaneous coronary intervention (PCI) patients. …"
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Microwave Imaging System for Non-Metallics Inspection in the Oil and Gas Industry
منشور في 2021احصل على النص الكامل
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A High‐Performance MPPT Solution for Solar DC Microgrids: Leveraging the Hippopotamus Algorithm for Greater Efficiency and Stability
منشور في 2025"…<p dir="ltr">The rapid growth of modern civilization has led to increased global warming and climate challenges. Variations in atmospheric temperature, sunlight intensity and other factors significantly impact the performance of photovoltaic (PV) systems. …"
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Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance
منشور في 2025"…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …"
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YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
منشور في 2025"…Accurately identifying small defects on PCB surfaces remains a considerable challenge, particularly under complex background conditions, due to the intricate and compact layout of the boards. …"
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Fault Diagnosis Based Machine Learning and Fault Tolerant Control of Multicellular Converter Used in Photovoltaic Water Pumping System
منشور في 2023"…<p dir="ltr">Currently, providing water in developing countries, especially in dry and hot rural areas, is a significant challenge. However, creating new electric grids is often expensive. …"