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posit models » probit models (توسيع البحث)
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posit models » probit models (توسيع البحث)
increased » increase (توسيع البحث)
decrease » increase (توسيع البحث)
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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The Conceptualization, Perceptions, and Practice of Positive Education in University Student Accessibility Departments
منشور في 2023"…The United Arab Emirates (UAE) is striving towards implementing a positive education model and positions education as a key element in measuring the nation’s success. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer
منشور في 2025"…Methods: In this investigation, we used cellular and molecular biology techniques in addition to an angiogenesis model and tissue microarray analysis. Results: Our data revealed that this combination therapy significantly reduced cell viability compared to individual treatments and exhibited a synergistic effect in HER2-positive BC cells. …"
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Diagnostic accuracy of interleukin-6 (IL-6) as a significant biomarker in late-onset neonatal sepsis: an updated systematic review and meta-analysis
منشور في 2025"…Pooled sensitivity and specificity were 85.2% (95% CI: 80.0–89.3%) and 84.1% (95% CI: 77.5–89.0%), respectively. The positive and negative likelihood ratios were 5.43 and 0.18, with a diagnostic odds ratio of 31.4. …"
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Source apportionment of PM₂̣ ₅ and PM₁₀ pollutants near an urban roadside site using positive matrix factorization
منشور في 2024"…Source apportionment was carried out using US Environmental Protection Agency (EPA) Positive Matrix Factorization model. Furthermore, backward trajectory analysis and Potential Source Contribution Function were used to assess air mass transport pathways and identify potential source regions, respectively. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Coexistence of negative and positive polarity electrostatic solitary waves in ultradense relativistic negative-ion-beam permeated plasmas
منشور في 2018"…It is shown that the coexistence of positive and negative potential pulses occurs in a certain interval of parameter values, where the ion beam inertia becomes significant.…"
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Investigation of positive education implementation and its impact on students' wellbeing and academic self-efficacy in K-12 private schools in Dubai
منشور في 2022"…The findings revealed the following: 1) in recent years there has been increasing positive education implementation grounding in the recent international, national, local, and educational authority policies and initiatives. 2) absence of standardised local and school policy related to positive education implementation has led to the need for adaptability of positive education implementation across school. 3) there has been strong engagement of the internal school community (teachers, school leaders and students) with external school community (parents). 4) significant changes in the overall level DSWC indicators associated with social emotional wellbeing, life satisfaction, perseverance, feeling safe, and belonging to school. 5) insignificant changes associated with DSWC indicators associated with emotional regulation, happiness, optimism, academic self-concept, cognitive engagement, engagement (flow), peer belonging and school climate. 6) PASS assessment factors show increase in wellbeing, motivation and self-efficacy for regulation and decrease in academic self-efficacy. 7) significant increase in emotional, social wellbeing and academic self-efficacy among students due to positive education implementation as perceived by teachers, parents, and students.…"
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Targeting HER2-positive breast cancer cells by a combination of dasatinib and BMS-202: Insight into the molecular pathways
منشور في 2024"…</p><h3>Conclusion</h3><p dir="ltr">Our findings implicate that a combination of DA and BMS-202 could have a significant impact on the management of HER2-positive breast cancer.…"
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Assessing uncertainty in image-based monitoring: addressing false positives, false negatives, and base rate bias in structural health evaluation
منشور في 2025"…The Base Rate Bias plays a significant role, as low probabilities of actual damage often lead to misinterpretation of positive results. …"
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Lower limb EMG activation during reduced gravity running on an incline. Speed matters more than hills irrespective of indicated bodyweight
منشور في 2021"…</p><h3>Results and significance</h3><p dir="ltr">Linear mixed models showed significant effect of running speed, inclination, and indicated bodyweight, with interaction effects observed. …"