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Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
منشور في 2021"…Our data showed that PAMAM dendrimers, mainly cationic types, significantly reduce cell viability in a dose-dependent manner. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Evaluation of The Factors Affecting Microplastics and Nanoparticles in Plastic Water Supply Pipes
منشور في 2020احصل على النص الكامل
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Positive Epstein-Barr virus polymerase chain reaction in a case of acute retinal necrosis
منشور في 2012"…He had panuveitis with significant vitreous haze and retinal necrosis nasally (Fig. 1). …"
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Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response?
منشور في 2019"…For the 3FOOT, there was a non significant decrease in postprandial TG AUC (-2.7%; p = 0.73; 95%CI = -2.0 to 1.5; ES = 0.05) and iAUC (-17.5%; p = 0.41; 95%ci = -2.5 to 1.1; ES = 0.31) from 10 to 34 hrs, respectively. …"
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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
منشور في 2011"…In vitro results largely confirmed these findings, as neither estrogen nor dihydrotestosterone affected LINE-1 or Alu methylation in Hek293T, HUVEC, or MDA-kb2 cell lines. …"
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Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
منشور في 2021"…Our data showed that PAMAM dendrimers, mainly cationic types, significantly reduce cell viability in a dose-dependent manner. …"
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
منشور في 2017"…Also, there was a significant decrease in p-Erk and p-Akt protein levels. …"
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
منشور في 2020"…In the chemoprevention study using rats, R. coriaria at a higher dose significantly reduced the tumor incidence by 20% and in lower dose non-significantly reduced tumor frequency by 29% when compared to controls. …"
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Why do some countries produce more capital intensive output than others?
منشور في 2016"…Based on my model I offer an explanation for the variation in physical capital intensity across countries where the model predictions show that a lower quality of governance in a country results in a decrease in the output of capital-intensive goods and an increase in the output of labor-intensive goods. …"
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Salvia officinalis water extract: a potential hypolipidemic, hypoglycemic and anti-ulcerogenic remedy
منشور في 2010"…Protection against ethanol-induced gastric ulcer [2] was investigated using 100 and 500mg/kg body weight doses. Results showed significant protection with both doses used. …"
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Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats
منشور في 2015"…The drug did not affect the number and composition of secreted very-low-density lipoprotein (VLDL) particles except for a decrease in VLDL TAG when the fat content in the diet was high. …"
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Board changes and CEO turnover
منشور في 2014"…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …"
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Effects of habitat complexity on the abundance, species richness and size of darkling beetles (Tenebrionidae) in artificial vegetation
منشور في 2016"…At the high levels of habitat complexity used in this study, the main effect of increasing complexity was excluding beetles from higher complexity treatments, particularly larger beetle species. The 6 mm (highest complexity) treatment had significantly lower abundance than the other three treatments. …"
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