-
1
-
2
-
3
-
4
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
-
5
How do gender and age similarities with a potential social engineer influence one’s trust and willingness to take security risks?
منشور في 2024"…While demographic similarity between the potential manipulator personas and participants did not significantly impact the participants trust and risk-taking, our study uncovered differences in trust and offer acceptance when both age and gender demographics were considered together, suggesting nuanced effects of demographic matching and mismatching on taking security risks. …"
-
6
Transforming Dermatopathology With AI: Addressing Bias, Enhancing Interpretability, and Shaping Future Diagnostics
منشور في 2025"…Despite its promise, challenges such as dataset biases, underrepresentation of diverse populations, and limited transparency hinder its widespread adoption. …"
-
7
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
-
8
-
9
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
-
10
Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials
منشور في 2024"…Study objectiveTraumatic injury causes a significant number of deaths due to bleeding. Tranexamic acid (TXA), an antifibrinolytic agent, can reduce bleeding in traumatic injuries and potentially enhance outcomes. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
11
Assessing uncertainty in image-based monitoring: addressing false positives, false negatives, and base rate bias in structural health evaluation
منشور في 2025"…However, its reliability is impacted by challenges such as false positives, false negatives, and environmental variability, particularly in low base rate damage scenarios. The Base Rate Bias plays a significant role, as low probabilities of actual damage often lead to misinterpretation of positive results. …"
-
12
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
13
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
14
Redox Homeostasis and Inflammation Responses to Training in Adolescent Athletes: a Systematic Review and Meta-analysis
منشور في 2020"…Following more extended training periods, GSH showed moderate increases (ES 1.131; 95% CI 0.350 to 1.913;<i>Z</i>= 2.839,<i>p</i>= 0.005) while TBARS displayed a small decrease (ES 0.568; 95% CI − 0.062 to 1.197;<i>Z</i>= 1.768,<i>p</i>= 0.077). …"
-
15
β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
منشور في 2017"…A significant decrease in protein levels of p53 and Bcl-2 and a significant increase in p21 and Bax were observed. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
16
The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France
منشور في 2018"…The results persist after running a matched-sample analysis and controlling for potential self-selection bias.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
17
The Economic Impact of Artificial Intelligence on Optimizing Drug Utilization and Reducing Waste in Outpatient Pharmacy Settings: A Meta-Analysis
منشور في 2023"…Despite some heterogeneity and potential publication bias, this analysis emphasizes the potential of AI applications to contribute to cost-effectiveness and sustainability in healthcare. …"
احصل على النص الكامل
-
18
The Role of Artificial Intelligence Technologies in Activating Educational Administration in the United Arab Emirates: An Applied Study on Private Schools in the Emirate of Sharjah
منشور في 2024"…However, challenges related to infrastructure, resources, and ethical considerations, including data privacy and potential bias, are acknowledged as potential barriers to effective AI adoption. …"
احصل على النص الكامل
-
19
-
20
Efficacy of mind maps and concept maps in enhancing academic performance among undergraduate medical students in the preclinical stage: a systematic review
منشور في 2025"…While not all studies showed significant differences, the overall preference for these methods indicates their potential as valuable learning tools. …"