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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Computational identification of genetic subnetwork modules associated with maize defense response to Fusarium verticillioides
منشور في 2015"…Based on our analysis pipeline, we identified four potential maize defense subnetwork modules. Two were directly associated with maize defense response and were associated with significant GO terms such as GO:0009817 (defense response to fungus) and GO:0009620 (response to fungus). …"
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<i>Ex Uno Plures</i>: Synecdoche as Argumentative Structure in Roman Defenses of Rhetoric
منشور في 2025"…<p dir="ltr">This essay explores synecdoche as an extended argumentative structure in Roman defenses of rhetoric. While contemporary scholarship often limits synecdoche to semantic substitution or distinguishes it from metonymy, theorists have recognized its potential as a form of argument. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"
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Antifungal activity of green synthesized selenium nanoparticles and their effect on physiological, biochemical, and antioxidant defense system of mango under mango malformation dis...
منشور في 2023"…The SeNPs at a concentration of 30 μg/mL were found to be the best concentration which enhanced the physiological (chlorophyll and membrane stability index), and biochemical (proline and soluble sugar) parameters. The antioxidant defense system was also explored, and it was reported that green synthesized SeNPs significantly reduced the biotic stress by enhancing enzymatic and non-enzymatic activities. …"
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
منشور في 2006احصل على النص الكامل
doctoralThesis -
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
منشور في 2025"…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…"
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YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
منشور في 2025"…Accurately identifying small defects on PCB surfaces remains a considerable challenge, particularly under complex background conditions, due to the intricate and compact layout of the boards. …"
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An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
منشور في 2022"…Additionally, the addition of vegetation alone had an impact on the microclimate decreasing it by 5%. Thus, combining the strategies of vegetation, shade, green facades/roofs and small water features resulted in 5% to 25% reduction in PET depending on the corresponding location being analyzed. …"
احصل على النص الكامل
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
منشور في 2021"…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
masterThesis -
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Phenotypic and Genotypic Characterization of Candida parapsilosis complex isolates from a Lebanese Hospital
منشور في 2023"…The azole fluconazole is the first line of defense in hospital treatment. Azoles function by inhibiting ERG11, an enzyme involved in the synthesis of ergosterol, the main sterol found in fungi. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
masterThesis -
20
Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia
منشور في 2006"…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
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