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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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The predictors of successful methotrexate treatment of tubal ectopic pregnancy
منشور في 2024"…Age, pre-treatment β-hCG levels, sonographic presence of yolk sac, presence of foetal cardiac activity, and pelvic pain were significantly different between patients with successful and unsuccessful outcomes. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Organizational factors that influence the success of IT projects
منشور في 2018"…The present document presents a comprehensive outlook of the influence of organizational factors on IT projects and their success. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Predictors, barriers, and facilitators to refugee women’s employment and economic inclusion: A mixed methods systematic review
منشور في 2024"…<div><p>Refugee women’s employment and economic inclusion have emerged as significant areas of focus, with these women facing unique challenges due to their gender, refugee status, and sociocultural identities. …"
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The influence of knowledge management practices on e-government success
منشور في 2018"…</p><h3>Findings</h3><p dir="ltr">Results have identified IT infrastructure and administrative issues as significant predictors of e-government projects’ success, where the relationship was mediated by KM practices. …"
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Factors Influencing Patient Conveyance Decisions by Ambulance Service Responders
منشور في 2024"…"Handover", the outcome variable (patient transported or not), and other predictors like socio-demographics and clinical information were assessed. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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The Influence of Performance Management Feedback on Employee Performance: The Moderating Role of Organizational Justice and its Dimensions (Procedural, Distributive, Interactional)
منشور في 2025"…In modern organizations, providing feedback is critical for increasing employee performance; nevertheless, little is known about how performance management feedback quality influences employee performance. Despite the extensive literature on performance management feedback and employee performance, it is not clear which justice predictors best account for greater employee performance. …"
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masterThesis