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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Rate Adaptation in Dynamic Adaptive Video Streaming Over HTTP
منشور في 2021احصل على النص الكامل
doctoralThesis -
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Training and Self-Rated Performance in the UAE Free Zones Context
منشور في 2012"…This dissertation study on “Training and Self-Rated Performance in the UAE Free zones Context” revolves around the objective or aim of exploring and validating the relationship between training and self-rated performance including the relationship between training and each of the six other important dimensions or areas for assessment on the individual employees’ work performance which include: “understanding of work duties”, “work skills”, “work enthusiasm”, “quality of work”, “quantity of work” and “readiness to innovate” where the final finding was that there is a significant relationship with each of the stated. …"
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
منشور في 2017"…For extension (%) at peak load, a decreasing trend was found vs. stretch rate (R2 = 0.81; two-tailed p value = 0.037) where increasing the displacement rate from 1 mm/min to 500 mm/min corresponds to a 22% decrease in the relative elongation of the mesh. …"
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conferenceObject -
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Breast Disease-Related Educational Outcomes at the University of Florida
منشور في 2000"…Residents who rotated on the breast service in the 6 months prior to the ABSITE had significantly fewer incorrect breast-related ABSITE questions than residents who had not rotated on the breast service. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Market Efficiency of Floating Exchange Rate Systems: Some Evidence from Pacific-Asian Countries
منشور في 2011"…For all other currencies the MDH is rejected at least for one benchmark over two periods, indicating that the market efficiency in these markets have not significantly improved under the floating rate systems following the Asian financial crisis.…"
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Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
منشور في 2020"…</p> <h2>Conclusion</h2> <p>Fall-related injuries remain as significant burden even in a level 1 trauma center. …"
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Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
منشور في 2010"…Results Median intra-operative blood loss was 250 cc, and 30-day peri-operative red cell transfusion rate was 27%. On multivariate analysis, factors that significantly predicted increased red cell transfusion rates were female sex, pre-operative hematocrit <30%, platelet count <100,000/mm3, simultaneous resection of other organs, major hepatic resection, use of the Pringle maneuver, and tumors >10 cm. …"
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Renal Nutrition-Related Knowledge, Dietary Compliance and Malnutrition among Hemodialysis Patients in Lebanon
منشور في 2023"…Weight loss was the most common phenotypic criterion among malnourished patients, while severe weight loss was significantly associated with poor compliance. Additionally, people with poor compliance tended to be younger (<55 years of age) and with lower levels of income and education (p<0.05) Conclusion and Recommendations: Malnutrition rates are alarmingly high among patients with ESKD in our sample and are significantly associated with poor treatment and dietary compliance. …"
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masterThesis