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The Role of Project Management Soft Skills in Increasing Project Success
منشور في 2017"…As the world economy shifts towards an increasingly globalised market, the degree of competition becomes a more significant challenge which organisations face. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"
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Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
منشور في 2016"…Interestingly, the expansion of peripheral GMCs correlated with higher stage and histological grade of cancer, thereby suggesting their role in cancer progression. Furthermore, an increase in CD33<sup>+</sup>CD11b<sup>+</sup>HLA-DR<sup>−</sup>CD14<sup>−</sup>CD15<sup>−</sup> immature myeloid cells was also observed in CRC tumor tissue. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …"
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk
منشور في 2015"…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …"
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Neither Neoadjuvant nor Adjuvant Therapy Increases Survival After Biliary Tract Cancer Resection with Wide Negative Margins
منشور في 2012"…Background We investigated the role of neoadjuvant/adjuvant therapies on survival for resectable biliary tract cancer. …"
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
منشور في 2019"…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"
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Perceptions and Views Regarding the Role of the Special Educational Needs and Disabilities Coordinators (SENDCos) and Challenges Affecting the Role in the United Arab of Emirates (...
منشور في 2017"…However, like many other countries, the UAE faces many significant social, cultural and financial challenges in the field of special education that would affect this role. …"
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Role of family in supporting children with mental disorders in Qatar
منشور في 2023"…Age has no statistically significant effect on the role of family members in supporting people with mental disorders.…"
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Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients
منشور في 2022"…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"
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The Role of Agile Leadership in Fostering Innovation in UAE Educational Institutions
منشور في 2024"…The findings indicate the significance and crucial role of agile leadership in the development and enhancement of better educational settings in the UAE, but there is a need for increased focus on agile leadership research to get a deeper understanding of agile leadership.…"
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Exploring the epigenetic landscape: The role of 5-hydroxymethylcytosine in neurodevelopmental disorders
منشور في 2024"…By examining mouse models, studies have demonstrated that prenatal environmental challenges, such as maternal infection and food allergies, lead to significant epigenetic alterations in 5hmC levels, which were associated with NDDs in offspring, impacting social behavior, cognitive abilities and increasing ASD-like symptoms. …"