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sup different » _ different (توسيع البحث)
increased » increase (توسيع البحث)
decrease » increase (توسيع البحث)
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Intratumoral FoxP3<sup>+</sup>Helios<sup>+</sup> Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer
منشور في 2017"…Levels of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> Tregs were significantly increased in the TME. …"
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Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"
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FoxP3<sup>+</sup> T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets
منشور في 2020"…We discuss the prognostic significance of FoxP3<sup>+</sup> Tregs in different cancers and their potential use as prognostic biomarkers. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Estimating hydrogen absorption energy on different metal hydrides using Gaussian process regression approach
منشور في 2022"…All the GPR models' performance was quite excellent; notably, GPR with Exponential kernel function showed the highest preciseness with R<sup>2</sup>, MRE, MSE, RMSE, and STD of 0.969, 2.291%, 3.909, 2.501, and 1.878, respectively. …"
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Playing Level and Position Differences in Body Characteristics and Physical Fitness Performance Among Male Team Handball Players
منشور في 2019"…The cross-sectional area for the first league players was also larger (p = 0.010, η<sup>2</sup><sub>p</sub> = 0.192). Regarding performance parameters, we found significant (p < 0.05 and η<sup>2</sup><sub>p</sub> > 0.20) league differences in five of 15 (33%) performance parameters: running throw (η<sup>2</sup><sub>p</sub> = 0.285), SJ power (η<sup>2</sup><sub>p</sub> = 0.670), SJ velocity (η<sup>2</sup><sub>p</sub> = 0.900), peak upper limb power (η<sup>2</sup><sub>p</sub> = 0.231) and Yo-Yo-IR 1 (η<sup>2</sup><sub>p</sub> = 0.348). …"
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Comparing metabolic profiles between female endurance athletes and non-athletes reveals differences in androgen and corticosteroid levels
منشور في 2022"…The results showed that, compared to non-athletic females, certain androgen, pregnenolone, and progestin steroid hormones were reduced in elite female endurance athletes, while corticosteroids were elevated. The most significantly altered steroid hormones were 5alpha-androstan-3alpha,17alpha-diol monosulfate (FDR = 1.90 × 10-<sup>05</sup>), androstenediol (3alpha, 17alpha) monosulfate (FDR = 2.93 × 10-<sup>04</sup>), and cortisol (FDR = 2.93 × 10-<sup>04</sup>). …"
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Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses
منشور في 2023"…No significant sex differences were present for the primary analysis of any outcome. …"
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The impact of different acidic conditions and food substrates on <i>Listeria </i><i>monocytogenes</i> biofilms development and removal using nanoencapsulated carvacrol
منشور في 2024"…However, at pH 5.5 and 6.5, increased biofilm levels were observed in both the culture media and food substrates, with the WT strain showing significantly higher biofilm formation (3.04–6.05 log CFU cm<sup>−2</sup>) than the mutant strains (2.30–5.48 log CFU cm<sup>−2</sup>). …"
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Estimation of Above-Ground Carbon-Stocks for Urban Greeneries in Arid Areas: Case Study for Doha and FIFA World Cup Qatar 2022
منشور في 2021"…The results of the analysis reveal that both the normalized difference vegetation index (NDVI) (R<sup>2</sup> = 0.64) and the relative ratio vegetation index (R<sup>2</sup> = 0.71) significantly correlate with the AGC in public parks. …"
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Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
منشور في 2024"…Expression of CaM<sup>D132E</sup> and CaMD134H mutants results in significant reduction of the zebrafish heart rate, mimicking a severe form of human bradycardia, whereas expression of CaM<sup>Q136P</sup> results in an increased heart rate mimicking human ventricular tachycardia. …"