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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Investigate stakeholders’ perceptions of best practices of STEM education in the United Arab Emirates
منشور في 2018"…The United Arab Emirates (UAE) is in the transition from an oil-based to a knowledge-based economy. …"
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A New Genetic-Based Tabu Search Algorithm For Unit Commitment Problem
منشور في 2020"…This paper presents a new algorithm based on integrating the use of genetic algorithms and tabu search methods to solve the unit commitment problem. …"
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Examining the perceptions and practices of undergraduate dental students and facilitators about Problem-based Learning (PBL) instructional approach in the United Arab Emirates
منشور في 2018"…One sample T test for the gender responses were T = - 0.620 and P-value = 0.535 showed no significant difference while One-way ANOVA were T = 4.518 and P-value = 0.001 found significant different between study level in problem-based Learning, ordered, as expected, as follows: Year 5 > Year 4 > Year 3 = Year 2 = Year 1. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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SoccerNet: A Gated Recurrent Unit-based model to predict soccer match winners
منشور في 2023"…We incorporated the highest number of professional matches from the last ten seasons covering from 2011 up to 2022 and proposed SoccerNet, a Gated Recurrent Unit (GRU)-based deep learning-based model to predict match winners with over 80% accuracy. …"
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Assessing the eco-environmental aspects of fossil fuels-based units substitution of Point Aconi thermal power plant by green-based energies: a case study of Canada
منشور في 2024"…This paper presents a model that replaces fossil fuels used in a proposed thermal power plant in Point Aconi, Nova Scotia, with photovoltaic and wind turbine units based on the region’s climate conditions. The research results are based on evaluating multiple thermal power plants worldwide and examining various wind turbines and PV panels from different companies to ensure accuracy. …"
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Optimum Design Model of Energy-Efficient Affordable Housing Units in UAE: Two Cases Study of Affordable Housing units in Dubai
منشور في 2020"…Moreover, the simulation results present that the models created based on the integration between the PV system technologies and passive design strategies significantly impact saving energy and reducing the life cycle cost of houses. …"
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Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project
منشور في 2024"…Medical devices contribute to approximately 50% of these total HAPI. HAPI is a significant patient safety issue in hospitalized patients and can lead to increased healthcare costs and a decreased quality of life for patients . …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Trends in Necrotizing Fasciitis‐Associated Mortality in the United States 2003–2020: A CDC WONDER Database Population‐Based Study
منشور في 2025"…</p><h3>Conclusions</h3><p dir="ltr">NF‐related mortality has significantly risen in the United States since 2014, with distinct disparities based on sex, race, and geographic region. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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