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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Toward a Clearer Understanding of Value‐Based Healthcare: A Concept Analysis
منشور في 2025"…<h3>Background</h3><p dir="ltr"> Value‐based healthcare (VBHC) aims to improve the quality of healthcare delivery while reducing costs and also aims for outcomes that are of utmost importance from patients’ perspectives. …"
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All in the value
منشور في 2018"…Purpose The purpose of this study is to test such effects on brands’ relationships and the perceived value of advertising. Social advertising featuring endorsed brands has significantly grown in the past few years. …"
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Interval-Valued SVM Based ABO for Fault Detection and Diagnosis of Wind Energy Conversion Systems
منشور في 2022"…Then, to improve even more the performances of the developed interval-valued SVM, multiscale data representation will be used to develop multiscale extensions of interval-valued SVM. …"
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Detection of statistically significant network changes in complex biological networks
منشور في 2017"…The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …"
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Gender differences in personal values
منشور في 2015"…Purpose – The purpose of this paper is to explore gender differences in personal values in an Arab country. Design/methodology/approach – Based on a sample of 137 participants, the Kruskal-Wallis test was used to identify if the mean scores or ranks of personal values scores were significantly different between males and females. …"
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Interval-Valued Reduced Ensemble Learning Based Fault Detection and Diagnosis Techniques for Uncertain Grid-Connected PV Systems
منشور في 2022"…Next, in order to more improve the diagnosis abilities, two interval kernel PCA (IKPCA)-based EL classifiers are developed. The IKPCA-EL techniques are addressed so that the features extraction and selection phases are performed using the IKPCA models and the sensitive and significant interval-valued characteristics are transmitted to the EL model for classification purposes. …"
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Application of TiO<sub>2</sub>-loaded fly ash-based geopolymer in adsorption of methylene blue from water: Waste-to-value approach
منشور في 2024"…<p dir="ltr">This paper aims to explore the removal of methylene blue from wastewater using fly ash-based geopolymer (FAG) modified with titanium dioxide (TiO<sub>2</sub>) <u>nanoparticles</u> referred to as FAG-TiO<sub>2</sub>. …"
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A Novel Steganography Technique for Digital Images Using the Least Significant Bit Substitution Method
منشور في 2022"…Therefore, the proposed work, in this paper, is based on the Least Significant Bit (LSB) substitution method. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"
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Promoter Ownership, Monitoring and Firm Value: Indian Evidence
منشور في 2025"…The analysis uncovers significant nonlinearities in the relationship between promoter ownership and firm value, as well as between banking relationships and firm value. …"
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Genetic Basis and Prognostic Value of Exercise QT Dynamics
منشور في 2020"…<h3>Background</h3><p dir="ltr">Abnormal QT interval responses to heart rate (QT dynamics) is an independent risk predictor for cardiovascular disease in patients, but its genetic basis and prognostic value in a population-based cohort have not been investigated.…"
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Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
منشور في 2023"…Furthermore, the panel discussed the needs to define value concerning cancer treatment in Qatar, implement value-based models for reimbursement decision-making such as health technology assessment and multiple-criteria decision analysis, and promote patient education and involvement/feedback in developing and implementing cancer management guidelines.…"
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