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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Toward a Clearer Understanding of Value‐Based Healthcare: A Concept Analysis
منشور في 2025"…<h3>Background</h3><p dir="ltr"> Value‐based healthcare (VBHC) aims to improve the quality of healthcare delivery while reducing costs and also aims for outcomes that are of utmost importance from patients’ perspectives. …"
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All in the value
منشور في 2018"…Purpose The purpose of this study is to test such effects on brands’ relationships and the perceived value of advertising. Social advertising featuring endorsed brands has significantly grown in the past few years. …"
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Interval-Valued SVM Based ABO for Fault Detection and Diagnosis of Wind Energy Conversion Systems
منشور في 2022"…Then, to improve even more the performances of the developed interval-valued SVM, multiscale data representation will be used to develop multiscale extensions of interval-valued SVM. …"
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Gender differences in personal values
منشور في 2015"…Purpose – The purpose of this paper is to explore gender differences in personal values in an Arab country. Design/methodology/approach – Based on a sample of 137 participants, the Kruskal-Wallis test was used to identify if the mean scores or ranks of personal values scores were significantly different between males and females. …"
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Detection of statistically significant network changes in complex biological networks
منشور في 2017"…The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Interval-Valued Reduced Ensemble Learning Based Fault Detection and Diagnosis Techniques for Uncertain Grid-Connected PV Systems
منشور في 2022"…Next, in order to more improve the diagnosis abilities, two interval kernel PCA (IKPCA)-based EL classifiers are developed. The IKPCA-EL techniques are addressed so that the features extraction and selection phases are performed using the IKPCA models and the sensitive and significant interval-valued characteristics are transmitted to the EL model for classification purposes. …"
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A Novel Steganography Technique for Digital Images Using the Least Significant Bit Substitution Method
منشور في 2022"…Therefore, the proposed work, in this paper, is based on the Least Significant Bit (LSB) substitution method. …"
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Promoter Ownership, Monitoring and Firm Value: Indian Evidence
منشور في 2025"…The analysis uncovers significant nonlinearities in the relationship between promoter ownership and firm value, as well as between banking relationships and firm value. …"
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Genetic Basis and Prognostic Value of Exercise QT Dynamics
منشور في 2020"…<h3>Background</h3><p dir="ltr">Abnormal QT interval responses to heart rate (QT dynamics) is an independent risk predictor for cardiovascular disease in patients, but its genetic basis and prognostic value in a population-based cohort have not been investigated.…"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"