SARS-CoV-2 Variants in Lebanon حسب Al Kodsi, Ibrahim

"…Mutations, especially in the S gene, defined viral fitness and caused the emergence and worldwide spread of variants. Variants of concern (VOC) included Alpha, Beta, Delta, Gamma, and most recently Omicron. …"
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The role of protective genetic variants in modulating epigenetic aging حسب Yosra Bejaoui (8552574)

"…In conclusion, APOE*E2 protective variants have a positive impact on epigenetic aging, while <i>PCSK9</i> protective variants have a significant effect on DNA methylation signatures. …"

The prevalence of the extensor digiti minimi tendon of the hand and its variants in humans حسب Yammine, Kaissar

"…However, it shows many variations in the human hand, which include splitting into two or more slips and sending a slip to the fourth finger, named the extensor digiti minimi et quarti (EDMQ). …"
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk حسب Merhi, Mahmoud

"…Results rs4769874 (ALOX5AP), rs854560 (PON1), and rs4646903 (CYP1A1 MspI polymorphism) are significantly associated with an increased risk of CAD with respective odds ratios of 1.53703, 1.67710, and 1.35520; the genetic variant rs9579646 (ALOX5AP) is significantly associated with a decreased risk of CAD (OR 0.76163). …"
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Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease حسب Sudharsana Sundarrajan (3181371)

"…The in silico pathogenicity prediction tools such as SIFT, Polyphen-2, Mutation Taster, CADD, LRT, PROVEAN, DANN, VEST3, fathmm-MKL, GERP + + , SiPhy, phastCons, and phyloP identified around 17 genes harbouring deleterious variants. The variants in the ALDH3A2 and RAD54B genes were pathogenic, while in 15 other genes were predicted to be variants of unknown significance. …"

Analysis of 14,392 whole genomes reveals 3.5% of Qataris carry medically actionable variants حسب Amal Elfatih (14778550)

"…Variants were categorized into one of the following groups: (1) Pathogenic (P), (2) Likely pathogenic (LP), and (3) Rare variants of uncertain significance with evidence of pathogenicity. …"

Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis حسب Maria K. Smatti (4675852)

"…Analysis of Qatari genomes revealed significantly lower AF of risk variants linked to SARS-CoV-1 severity (CCL2, MBL, CCL5, AHSG, and IL4) compared to that of 1000Genome and/or the EAS population (up to 25-fold change). …"

Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping حسب Karsten Suhre (67967)

"…We identify 184 protein-altering variants in 137 genes that are significantly associated with their corresponding variant peptides, confirming target specificity of co-associated affinity binders, identifying putatively causal cis-encoded proteins and providing experimental evidence for their presence in blood, including proteins that may be inaccessible to affinity-based proteomics.…"

Genetic evaluation of cardiomyopathies in Qatar identifies enrichment of pathogenic sarcomere gene variants and possible founder disease mutations in the Arabs حسب Kholoud N. Al‐Shafai (18459009)

"…</p><h3>Conclusion</h3><p dir="ltr">We identified or replicated at least four recurrent variants among cardiomyopathy patients, which could be founder disease mutations in the Arabic population, including a frameshift variant (c.1371_1381dupTATCCAGTTAT) of unknown significance in the FKTN gene which seems to cause DCM in homozygosity, and HCM in heterozygosity. …"

Spectrum of genetic variants associated with maple syrup urine disease in the Middle East, North Africa, and Türkiye (MENAT): a systematic review حسب Salma Younes (6424865)

"…</p><h3>Aim</h3><p dir="ltr">This study aimed to systematically review the variants significantly associated with MSUD in the MENAT region.…"

Successful bone marrow transplantation in a patient with Omenn syndrome, a rare variant of severe combined immunodeficiency syndrome: A case report حسب Ubaid Khan (12476186)

"…Pre‐transplant conditioning included antimicrobial prophylaxis and supportive therapies. …"

Associations between telomere attrition, genetic variants in telomere maintenance genes, and non-small cell lung cancer risk in the Jammu and Kashmir population of North India حسب Gh. Rasool Bhat (6701726)

"…</p><h3>Results</h3><p dir="ltr">Our findings revealed significant associations of TERT rs10069690 and POT1 rs10228682 with NSCLC risk (adjusted p-values = 0.019 and 0.002, respectively), while TERF2 rs251796 and rs2975843 showed no significant associations. …"

Role of previous infection with SARS-CoV-2 in protecting against omicron reinfections and severe complications of COVID-19 compared to pre-omicron variants: a systematic review حسب Maryam Arabi (3927509)

"…The aim of this review is to understand the effectiveness of previous infection on subsequent reinfection, given its significance in driving public health policy, including vaccination prioritization and lockdown requirements.…"

Alpelisib Therapy in 2 Patients With Congenital Hyperinsulinism حسب Khalid Alburshad (22467244)

"…In both cases, alpelisib significantly improved glucose levels, reducing the frequency of hypoglycemic episodes. …"

Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study حسب Mona Abdi (10196665)

"…Dominant variants, including de novo and inherited, contributed to 15 (55.6%) of these families, consisting of SNVs/indels (66.7%), CNVs (13.3%), TREs (13.3%), and mtDNA variants (6.7%). …"

Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches حسب ALHAJERI, RASHED ABDULLA

"…Solar energy has the largest untapped reserve in energy and is one of the fastest emerging energy markets. …"
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Effect of consanguinity on birth weight for gestational age in a developing country حسب Wakim, Gerard

"…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …"
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo حسب Daaboul, Hamid E.

"…Also, there was a significant decrease in p-Erk and p-Akt protein levels. …"
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Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data حسب Squalli, Jay

"…After controlling for other sources of emissions, U.S. states that produce a larger share of renewable energy are found to have lower GHG emissions. …"
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Association of genetic polymorphisms in FTO with Overweight/Obesity and Type 2 Diabetes in the Lebanese Population حسب Maroun, Veronica

"…On the other hand, the studied FTO variants were not significantly associated with T2DM. …"
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