Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros حسب Mesmar, J.

"…In addition, ZNE significantly decreased the migratory and invasive capacity of Capan-2 with a concomitant downregulation of integrin α2 and increased cell–cell aggregation. …"
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Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening حسب Shurbaji, Samar Haroon

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Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening. حسب Shurbaji, Samar

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NADPH-derived ROS generation drives fibrosis and endothelial-to-mesenchymal transition in systemic sclerosis: Potential cross talk with circulating miRNAs حسب Posadino, Anna Maria

"…Sera from SSc patients showed significant changes in the expression of a set of fibrosis/EndMT-associated microRNAs (miRNA), including miR-21, miR-92a, miR-24, miR-27b, miR-125b, miR-29c, and miR-181b, which resulted significantly upregulated as compared to healthy donors sera. …"
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Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia حسب Kuttikrishnan S.

"…Sang mediates its anti-cancer activity by generation of reactive oxygen species (ROS) due to depletion of glutathione level in leukemic cell lines. …"
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells حسب Zibara, Kazem

"…Furthermore, PACAP induced ROS through H₂O₂ production whereas pretreatment with NAC inhibitor decreased AKT and ERK phosphorylation, but not p38. …"
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Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties حسب Mesmar, Joelle

"…Non-cytotoxic concentrations of OSEE attenuated cell proliferation and induced G0/G1 cell cycle arrest, which was associated with phosphorylation of p38 MAPK, an increase in the levels of tumor suppressor protein p21, and a decrease of proliferation marker protein Ki67. Additionally, only higher concentrations of OSEE were able to attenuate inhibition of proliferation induced by the ROS scavenger N-acetyl cysteine (NAC), indicating that the anti-proliferative effects of OSEE could be ROS-dependent. …"
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro حسب Rizk, Nasser Moustafa

"…This study demonstrated that hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis. eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours. …"
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ASSOCIATION BETWEEN INSULIN RESISTANCE AND NITRIC OXIDE IN HUMAN RETINAL MICROVASCULAR ENDOTHELIAL CELLS IN VITRO حسب Bushra, Sumbul

"…This study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably reduced with insulin treatment after 1hour, 2 hours and 4 hours. …"
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Uncovering the Epigenetic Contribution of Protein Arginine Methyltransferase 5 (PRMT5) during Zebrafish Cardiomyogenesis حسب Zakaria, Zain Zaki

"…This was accompanied by a moderate decrease in blood flow (20%), significantly higher decrease in general cardiac output (65%), and reduction in red blood cells count (50%). …"
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Concentration of sucrose solutions via vacuum membrane distillation حسب Al-Asheha, S.

"…The increase in the initial sucrose concentration resulted in a slight decrease in the flux without affecting the quality of the permeate. …"
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Individual and Synergic Effects of Phosphorus and Gibberellic Acid on Organic Acids Exudation Pattern, Ultra-Structure of Chloroplast and Stress Response Gene Expression in Cu-Stre... حسب Alatawi, Aishah

"…Results revealed that C. capsularis tolerated up to 200 mg kg−1 Cu concentration without a significant (P < 0.05) decrease in biomass, plant height and root length but further increase in Cu concentration from 400 mg kg−1 exhibited a significant reduction in plant height, root length, stem fresh weight, stem dry weight, plant fresh weight and plant dry weight. …"
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Wind energy potential along the onshore and offshore Qatar حسب Mohammed, Aboobacker Valliyil

"…The results show that there is no signi?cant increase or decrease of wind power around Qatar in the last 40 years in most of the locations, while there is a slight decreasing trend in the o?…"
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Effects Of Gamma Radiation On The Mating Activity Of The Mediterranean Fruit Fly. Ceratitis Capitata Weid حسب Wakid, A. M.

"…However, at 90 gray, the mating of the irradiated males were significantly less than normal males. The mating ability of the irradiated males with normal females was decreased with increasing the dose. …"
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Optimizing nutrient removal of moving bed biofilm reactor process using response surface methodology حسب Almomani F.

"…Reactors demonstrated stable biofilm characteristics except for a slight decrease in biofilm thickness due to flow-shear stress. …"
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Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes حسب Younes, Noura B.

"…In addition, DHA-treatment of hypoxic cells caused a significant reduction in the apoptosis rate and ROS production with decreased lipid peroxidation. …"
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Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes حسب Younes, Noura B.

"…Results: Under hypoxia conditions, DHA treatment resulted in significant changes in all critical parameters of adipocyte biology including HIF-1α RNA expression (decreased by 50%), decreased lactate and glycerol release (66% and 25% respectively), and reactive oxygen species (ROS) production (decreased by 15%), while glucose uptake was decreased by 25% accompnied by decreased secretion of pro-inflammatory markers (Interleukin 6 IL-6, 31% reduction) , macrophage chemoattractant protein 1 MCP-1 (38% reduction) and leptin (14% reduction), and increased adiponectin secretion (by 45%). …"
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Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation حسب Feng, Samuel

"…Mitochondrial ATP production is the main source of reactive oxygen species (ROS) and hence the regulation of ROS becomes an important issue in maintaining optimal ANS functionality. …"
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Trends of use of SGLT2 inhibitors in Qatar حسب Zaghloul, Nancy

"…SGLT2is use increased over the years after being introduced to the formulary in 2017, replacing SUs which exhibited significant decline between 2017 and 2020. There was a slight reduction in metformin use, and a slight increase in DPP-4is use. …"
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Optimization of performance and emission characteristics of CI engine fueled with Jatropha biodiesel produced using a heterogeneous catalyst (CaO) حسب Singh, A.

"…In present investigation has witnessed a significant decrease in HC emissions (14.29 percent) compared to diesel, and a slight increase in NOx emissions (1.98 percent) is also observed. …"
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