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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Online Feedback in a Visible Learning School: An Investigation to Study the Effect of Online Feedback during Online Sessions Conducted through Nearpod
منشور في 2022"…Since feedback is one of the most significant elements that support the learning process and online learning is a demand nowadays, the present study utilizes a mixed methodology to investigate the effect of online feedback that is conducted through Nearpod during online sessions in one of the private schools in Sharjah, UAE that implements the visible learning principles. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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The advent of the ‘social moment of truth’ in online communities
منشور في 2017"…Concurrently, retailers have significantly increased their social presence to influence shoppers’ buying decisions. …"
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Creating and detecting fake reviews of online products
منشور في 2022"…<p>Customers increasingly rely on reviews for product information. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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The Role of English Online Gaming in Developing L2 Students' Speaking Fluency
منشور في 2024"…The rapid development and widespread adoption of online gaming platforms have garnered significant academic interest, particularly concerning their impact on students’ English language development and verbal communication skills. …"
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A Novel Deep Learning Technique for Detecting Emotional Impact in Online Education
منشور في 2022"…Detecting student emotions can significantly increase productivity and improve the education process. …"
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Role of shared identity and agency trust in online voting among Finnish citizens
منشور في 2023"…We found that citizens’ perceptions of shared identity with online voting agencies significantly contribute to agency trust. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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Mixed precision iterative refinement with adaptive precision sparse approximate inverse preconditioning
منشور في 2025"…<p dir="ltr">Hardware trends have motivated the development of mixed precision algorithms in numerical linear algebra, which aim to decrease runtime while maintaining acceptable accuracy. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"