Neither Neoadjuvant nor Adjuvant Therapy Increases Survival After Biliary Tract Cancer Resection with Wide Negative Margins حسب Glazer, Evan

"…Immediate resection increased median survival from 42.3 to 53.5 months (p = 0.01). …"
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Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation حسب Zreik, Tony

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Nuancing the double and triple nexus: analyzing the potential for unintended, negative consequences حسب Logan Cochrane (7822049)

"…<p dir="ltr">International and national actors are increasingly calling for a double or triple nexus approach to humanitarian, development, and peace activities to improve the flexibility of programming, particularly in complex crises. …"

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis حسب Osama Hussein (21301202)

"…In conclusion, standalone phacoemulsification significantly lowers IOP and reduces the need for glaucoma medications in patients with glaucoma.…"

Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes حسب Rizk, Sandra

"…Conclusion: In conclusion, kefir is effective in inhibiting proliferation and inducing apoptosis of HTLV-1-negative malignant T-lymphocytes. Therefore, further in vivo investigation is highly recommended.…"
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Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity حسب Ayman Alzu’bi (13162392)

Phospholipase C negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells حسب El-Sibai, Mirvat

"…These data suggest that PLCc is involved in a negative feedback loop that leads to the inhibition of Rac and Cdc42. …"
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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …"

Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study حسب Mostafa Najim (14150400)

"…<p>Coronavirus disease 2019 (COVID-19) increases the risk of coagulopathy. Although the presence of antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism of COVID-19-induced coagulopathy, its clinical significance remains uncertain. …"

Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation حسب Mahéva Vallet (18456729)

"…We conclude that Rin3 negatively regulates trabecular bone mass in mice by inhibiting osteoclastic bone resorption and favouring bone formation. …"

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway حسب Olfa Khalifa (10914452)

Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease حسب Nour K. Majbour (8809316)

"…CSF total α-syn (t-α-syn) significantly increased in the AD group (p < 0.0001) compared to controls, while oligomeric- and phosphorylated-Ser129-α-syn did not change significantly. …"

The Paget's disease of bone risk gene <i>PML</i> is a negative regulator of osteoclast differentiation and bone resorption حسب Sachin Wani (11704868)

Long-term antibiotic resistance surveillance of gram-negative pathogens suggests that temporal trends can be used as a resistance warning system حسب Sorberg, Mikael

"…The analysis of resistance levels and antibiotic consumption in the present study suggests different mechanisms for the increased resistance. The significant trend of increased resistance to antibiotics over time constitutes an important warning system.…"
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PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer حسب Reem Saleh (3513056)

"…<div><p>Triple negative breast cancer (TNBC) is the most aggressive type of breast cancer, which shows resistance to common breast cancer therapies, as it lacks the expression of the most common breast cancer targets. …"

The Anti-Cancer Effect of Strained Photoactivatable Polypyridyl Ruthenium(II) Complexes on Non-Small-Cell Lung Cancer and Triple Negative Breast Cancer Cells حسب Fayad, Christelle

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The anti-cancer effect of series of strained photoactivatable Ru(II) polypyridyl complexes on non-small-cell lung cancer and triple negative breast cancer cells حسب Fayad, Christelle

"…It also significantly increased Bax/Bcl2 ratio and PERK levels without affecting caspase-3 expression. …"
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The effect of Inula Viscosa extract on inflammation, microbial growth, glycemia, and blood lipid profile. (c2005) حسب Zaza, Rola Mouin

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