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The Experience of Palliative Care Nurses in Qatar During the Time of COVID-19: A Qualitative Study
منشور في 2023"…Twenty-two nurses working in a palliative care unit participated in this study. Data were collected during 1.5- to 2-hour focus group sessions that were guided by open-ended questions.…"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Sex differences in shoulder performance fatiguability are affected by arm position, dominance and muscle group
منشور في 2022"…</p><h3>Results</h3><p dir="ltr">Muscle group was the only factor to display significant variation when not considering other factors, with higher values for C.Perf (mean difference = 353.59 J, <i>P </i>< 0.0005), BR (mean difference = 14.21 J, <i>P </i>< 0.0005) and IF (mean difference = 3.65%, <i>P </i> = 0.0046). …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"
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Unlocking Team Dynamics: Exploring the Influence of Group Regulation on Technical Development in Small-Sided Soccer Games
منشور في 2024"…</p><h3>Results</h3><p dir="ltr">The results showed no significant differences in the main effects of the time, group, session, and group × session × time interactions for most technical actions. …"
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Implications on Educational Management During the COVID-19 Pandemic
منشور في 2021"…Education sector faced a significant transition recently, shifting from face-to-face classes to online classes due to the unprecedented COVID-19 pandemic. …"
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Implications on Educational Management During the COVID 19 Pandemic
منشور في 2021"…Education sector faced a significant transition recently, shifting from face-to-face classes to online classes due to the unprecedented COVID-19 pandemic. …"
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Carbon dioxide insufflation during ERCP for reduction of postprocedure pain
منشور في 2009"…Adverse events were infrequent and did not differ by group. No serious cardiopulmonary complications occurred. …"
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Exergames versus self-regulated exercises with instruction leaflets to improve adherence during geriatric rehabilitation: a randomized controlled trial
منشور في 2017"…Adverse effects were observed in two patients in the EG who stopped because of pain during exercising. Adherence was comparable at day one (38 min. in the EG and 42 min. in the CG) and significantly higher in the CG at day 10 (54 min. in the CG while decreasing to 28 min. in the EG, <i>p</i> = 0.007, ES 0.94, 0.39–0.151). …"