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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Self-reported awareness and attitude of cancer patients towards clinical nurse coordinators
منشور في 2017"…Methods: This is a cross sectional study that was conducted by distributing a self-reported and anonymous survey to 240 cancer patients visiting the center. …"
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Development, Characterization and In Vitro Evaluation of Cannabidiol Loaded Zeolite Nanoparticles
منشور في 2025"…In addition, Cell Uptake studies demonstrated an increase in CBD internalization and retention by 2.4 folds for the USY loaded zeolite and 1.9 folds for the MCM-41 loaded zeolite when compared to CBD in its free form. …"
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masterThesis -
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Optimal Planning of Distributed Generators and Shunt Capacitors in Isolated Microgrids With Nonlinear Loads
منشور في 2020"…The effectiveness of the proposed planning approach has been validated using the PG&E 69-bus system, and the followings are observed: 1) the significance of applying suitable fundamental-power-flow and harmonic-power-flow algorithms for isolated microgrids, and 2) the possibility of avoiding a severe voltage distortion by utilizing an appropriate planning method and only small increase in the cost.…"
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Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients
منشور في 2021"…<h3>Background</h3><p dir="ltr">The management of chronic kidney disease (CKD) and its complications places a significant burden on patients, resulting in impairment of their health-related quality of life (HR-QOL). …"
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Behavior Of Reinforced Concrete Columns Embedded with PET Bottles Under Concentric Axial Compression
منشور في 2025احصل على النص الكامل
doctoralThesis -
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Effect of Girder Damage on the Structural Behavior of Slab-on-Girder Bridges
منشور في 2011احصل على النص الكامل
doctoralThesis -
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Comparative Study of the Structural Behaviour of Cast Acrylic & Laminated Glass Under the Impact of Dynamic Loading in Aquatic Applications
منشور في 2023"…Finally, CA sheets recorded slightly lower deflection values than it was in LG under the increasing effect of hydrostatic pressure (collision depth) and eventually showed almost a constant behavior of stress but significantly lower than those recorded in LG sheets.…"
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Electric Vehicles Charging Station Load Forecasting Integration With Renewable Energy Using Novel Deep EfficientBiLSTMNet
منشور في 2025"…<p dir="ltr">The exponential increase in the adoption of Electric Vehicles (EVs) presents significant problems to the stability of the power grid. …"
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The Effect of Auditor Characteristics on the Quality of Segment Disclosures of Diversified Firms
منشور في 2024احصل على النص الكامل
doctoralThesis -
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FEA Investigation of Elastic Buckling for Functionally Graded Material (FGM) Thin Plates with Different Hole Shapes under Uniaxial Loading
منشور في 2022"…The results show that the increase in the size of the opening and the aspect ratio reduces the critical buckling load of the FGM plate. …"
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Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
منشور في 2018"…The reduction of 1.9 ͦ C in outdoor air temperature, and 4.9 % in cooling load is achieved by increasing the H/W ratio of the main canyons from 0.96 to 1.2. …"
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Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
منشور في 2023"…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. However, the cancer-related burden on patients, healthcare systems, and the economy is expected to expand; thus, cancer remains a significant public healthcare issue in Qatar. …"
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Students Plugged: The Psychological Impact of Smart Devices Screen Time Exposure on Cognitive Concentration Skills in Primary School Students in Abu Dhabi
منشور في 2025"…Keywords: screen time, cognitive skills, physical activity, selective attention, divided attention, social interaction, mental health, cognitive load theory…"
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Non-diabetic ketoacidosis secondary to primary hyperthyroidism
منشور في 2022"…This was associated with decreased appetite and weight loss.</p><h3>Diagnosis</h3><p dir="ltr">Laboratory findings were significant for high anion gap metabolic acidosis, positive ketones in the urine, and high serum B-hydroxybutyrate. …"