Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis حسب Allgayer, Heike

"…BACKGROUND The specific activity of the non-receptor protein tyrosine kinase, Src, is increased in the majority of colon and rectal adenocarcinomas compared to normal mucosa. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia حسب Shilpa Kuttikrishnan (3520079)

Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... حسب Masri, Oussama Samer

"…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas... حسب Basala, Sobhiya

"…Following cell entry, LF cleaves all mitogen- activated protein kinase kinase (MEKs) leading to the inactivation of the MAPK pathway. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia حسب Hend Salah Fayed (17732622)

"…At the histological level, we found that GSK429286 significantly increased the size of new microvessels in the regenerating areas of ischemic muscles compared with vehicle-treated ones. …"

The Effect of Recombinant Anthrax Lethal Toxin on Breast Cancer Cell Motility, Adhesion, and Invasion حسب El Chami, Dana

"…Additionally, cells treated with LT showed an increase in adhesion, decrease in invasion across a collagen matrix, and in increase in Rho A activation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... حسب Farhat, Mirna

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Safety of Novel Therapies in Chronic Lymphocytic Leukemia in the Era of Intermittent Fasting: A Pharmacology-Based Review حسب Maria Benkhadra (19756941)

"…Concurrently, novel agents (NAs) like venetoclax and Bruton tyrosine kinase inhibitors (BTKIs) have revolutionized the treatment of chronic lymphocytic leukemia (CLL). …"

Mechanical stretch and prostaglandin E2 modulate critical signaling pathways in mouse podocytes حسب Faour, Wissam

"…Finally, mechanical stretch alone or in combination with HG, induced ERK1/2 and JNK activation, via the EGF receptor since AG1478, a specific EGF receptor kinase inhibitor, blocked this activation. These results show that cellular signaling in podocytes is significantly altered under diabetic conditions (i.e., hyperglycemia and increased Pgc). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension حسب Thiruveni Ramkumar (17075051)

"…On the other hand, neonates of hypertensive mothers administered with methyldopa showed a significant decrease of initial blood glucose reading.…"

Self-reported awareness and attitude of cancer patients towards clinical nurse coordinators حسب Deeb, Ahmad

"…Responses on Likert scales were converted to percentage mean scores. Results: The overall percentage mean scores ± standard deviation of knowledge was 59 ± 17, perception towards clinical nurse coordinators (79 ± 14) and attitude towards seeking their services (69 ± 16). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema حسب Diab, Khalil J.

"…Measurements and Main Results: Consistent with previously reported de novo activation of ceramide synthesis, VEGFR inhibition triggered increases in lung ceramides, dihydroceramides, and dihydrosphingosine, but did not alter sphingosine kinase activity or S1P levels. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained? حسب Wahiba Elhag (5245547)

"…Mean HbA1c significantly decreased from 8.1%preop to 6.77%_{year 9}. …"

Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases حسب Hirbli, K.

"…Following treatment of the hyperthyroidism, control was improved in 63%, with an 11-83% (mean 44%) decrease in insulin dosage in 59% of them. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition حسب Bouclaous, Carmel

"…Prednisolone-treated groups revealed significantly lower intestinal absorption. However, prednisolone-treated high-carbohydrate (HC) fed rats showed significantly higher weight gain, concomitant with a significant increase in feed efficiency. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Renal Function Decline in Recipients and Donors of Kidney Grafts حسب Bahous, Sola Aoun

"…Results: Decline in renal function was estimated at 1-year post-transplantation and annually thereafter (median follow-up 8 years, range 3.6-18.3), as the mean of the annualized decrease in the glomerular filtration rate. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats حسب Azar Hosseini (33501)

"…Despite available drugs, there is still an increased need to look for alternative therapies or identify new bioactive compounds. …"

Effect of acute and chronic grapefruit, orange and pineaple juice consumption upon blood lipoprotein synthesis and metabolism in the rat. (c2004) حسب Abou-Khalil, Jamil

احصل على النص الكامل
احصل على النص الكامل

Nurses’ work environment and intent to leave in Lebanese hospitals حسب Dimassi, Hani

"…Results The NWI-R subscale with the lowest mean score related to control. Younger nurses had lower scores on organizational support and career development. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Rescue cerclage حسب Khoury, Alfred

"…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل