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The relationship between sleep duration and health status in Qatar’s population
منشور في 2020"…Qatar’s population exhibited high prevalence of short sleep duration, which was significantly associated with poor rated health, obesity, and chronic illness independent of age, gender, or social class.…"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Adapting to Climate Risk? Local Population Dynamics in the United States
منشور في 2024"…We also find that the agglomeration is largely driven by increases in the (white) working-age population. In addition, we show that high-risk tracts have typically grown more than low-risk tracts <i>within</i> the same county, suggesting the presence of highly localized amenities. …"
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Country of birth affects blood pressure in the French hypertensive diabetic population
منشور في 2015"…In a population of 56,242 individuals living in France, we showed that individuals born in France have significantly different levels of blood pressure (BP) and cardiovascular (CV) risk factors than African and Asian populations born in their own country but living long-term in France (average duration of stay, 5–10 years). …"
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Landscape of childhood epilepsies – A multi-ethnic population-based study
منشور في 2022"…</p><h3>Significance </h3><p dir="ltr">This large multi-ethnic population-based study confirms that the prevalence, incidence and clinical features of epilepsy in Qatar is in accordance with other epidemiologic studies and highlights risk factors for the development of co-morbidities and medically-intractable epilepsy.…"
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Maternal and Neonatal Outcomes Post Bariatric Surgery: A Population-Based Study
منشور في 2023"…On the other hand, obesity significantly increased the risk of gestational diabetes, cesarean deliveries, and labor induction in comparison to the other groups.…"
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The hazardous impacts of mining activities on population's health in Blue Nile State - Sudan
منشور في 2014"…Serum level of chromium in the Jam area population was P < 0.05, copper and cobalt were P>0.05; and the values were found to be in normal reference range, except for chromium which was found to be slightly increased in Jam area. …"
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Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population
منشور في 2014"…Results: The prevalence of T2DM significantly increased with increasing BMI (p < 0.0001). …"
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Association of genetic polymorphisms in FTO with Overweight/Obesity and Type 2 Diabetes in the Lebanese Population
منشور في 2021"…Conclusion: The rs17817499 variant of the FTO gene was highly associated with overweight and obesity in the Lebanese population. On the other hand, the studied FTO variants were not significantly associated with T2DM. …"
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National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050
منشور في 2024"…The prevalence of obesity has outpaced the increase in overweight over time, especially among adolescents. …"
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