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Oral Food Challenge Protocols in Food Protein-Induced Enterocolitis Syndrome: A Systematic Review
منشور في 2025"…<h3>Background</h3><p dir="ltr">Oral food challenges (OFCs) are essential for the diagnosis and follow-up of acute food protein-induced <u>enterocolitis</u> syndrome (FPIES) because no diagnostic or prognostic biomarkers are available. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Impacts of COVID-19 pandemic on environment, society, and food security
منشور في 2023"…At the world level, it increased risks to food safety by increasing prices and lowering revenues, forcing households to reduce their food consumption in terms of quantity and quality. …"
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Mixed precision iterative refinement with adaptive precision sparse approximate inverse preconditioning
منشور في 2025"…<p dir="ltr">Hardware trends have motivated the development of mixed precision algorithms in numerical linear algebra, which aim to decrease runtime while maintaining acceptable accuracy. …"
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Environmental Impact Assessment of Food Waste Management Using Two Composting Techniques
منشور في 2020"…<p dir="ltr">Food waste is a significant contributor to greenhouse gas emissions (GHG) and therefore global warming. …"
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Biochar development from thermal TGA studies of individual food waste vegetables and their blended systems
منشور في 2022"…<p>The amount of food waste that is generated all over the world is enormous. …"
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Optimum sustainable utilisation of the whole fruit of Jatropha curcas: An energy, water and food nexus approach
منشور في 2021"…In this context, biomass has increased in popularity and acquired a significant share of the global energy mix in a relatively short time. …"
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Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women
منشور في 2021"…In a continuous variable analysis, the association between 25(OH)D and bone mass was significant, non-linear, inverse ‘U’. In conclusion, serum 25-hydroxyvitamin D was inversely associated with adiposity measures and non-linearly associated to bone mass in postmenopausal Qatari women.…"
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Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women
منشور في 2021"…In a continuous variable analysis, the association between 25(OH)D and bone mass was significant, non-linear, inverse ‘U’. In conclusion, serum 25-hydroxyvitamin D was inversely associated with adiposity measures and non-linearly associated to bone mass in postmenopausal Qatari women.…"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
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Analyzing the Influence of Climate and Anthropogenic Development on Vegetation Cover in the Coastal Ecosystems of GCC
منشور في 2025"…Our results revealed significant changes in land cover, as seen by an increase in artificial built-up areas by 15.5% in two decades and a corresponding decrease in bareland and dense vegetation. …"