Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy حسب Jia-Zhen Wu (6844793)

"…The chaperone-mediated autophagy (CMA) pathway is involved in the intracellular degradation processes of α-synuclein. …"

The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells حسب Maram Hasan (6672440)

Genetic distribution of natural killer receptors (killer immunoglobulin-like receptors) in familial mediterranean fever, recurrent tonsillitis and lymphoma in lebanese patients. (c... حسب Sabbagh, Amira Samir

احصل على النص الكامل
احصل على النص الكامل

Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine حسب Hamda A. Al-Naemi (14151675)

"…Exposure to Cd increases the risk of cardiovascular disease by disrupting vascular homeostasis at the endothelium. …"

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed حسب Bartholomew, Aaron

احصل على النص الكامل

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

Cytokine-Mediated Dysregulation of Signaling Pathways in the Pathogenesis of Multiple Myeloma حسب Sabah Akhtar (5809925)

Evaluation of The Factors Affecting Microplastics and Nanoparticles in Plastic Water Supply Pipes حسب Hammodat, Amina Rayan

احصل على النص الكامل

The efficacy of colchicine in the management of coronavirus disease 2019 حسب Mohamed Nabil Elshafei (9960500)

"…If colchicine proved to be effective, it would be a significant milestone in the management of COVID-19, a disease with limited available therapeutic options.…"

How global spine sagittal alignment and spinal degeneration affect locomotive syndrome risk in the elderly حسب Ramada R. Khasawneh (6837734)

Towards the development of an integrated model for examining the determinants affecting the use of Queue Management Solutions in Healthcare حسب ALQUDAH, ADI AHMAD ALI

احصل على النص الكامل

Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response? حسب Darren J. Paul (6905450)

"…For the 3FOOT, there was a non significant decrease in postprandial TG AUC (-2.7%; p = 0.73; 95%CI = -2.0 to 1.5; ES = 0.05) and iAUC (-17.5%; p = 0.41; 95%ci = -2.5 to 1.1; ES = 0.31) from 10 to 34 hrs, respectively. …"

Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles حسب El Maarri, Osman

"…In vitro results largely confirmed these findings, as neither estrogen nor dihydrotestosterone affected LINE-1 or Alu methylation in Hek293T, HUVEC, or MDA-kb2 cell lines. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Anthracyclines-Induced Vascular Endothelial Dysfunction in Cancer Patients and Survivors Using Brachial Flow-Mediated Dilation (FMD) Tool: A Systematic Review and Meta-Analysis حسب Lana A. Kattan (22466173)

"…Brachial flow-mediated dilation (FMD) is a non-invasive technique for evaluating vascular endothelial function. …"

Three cases of chronic photodermatitis successfully treated with upadacitinib حسب Hissa Al-Marri (22827287)

"…<p dir="ltr">Photodermatoses represent a varied collection of skin disorders characterized by cutaneous reactions provoked by exposure to ultraviolet radiation. The disease mechanism is based on an immune-mediated delayed hypersensitivity reaction. …"

Osteoarthritis: a narrative review of molecular approaches to disease management حسب Loay A. Salman (14150322)

"…While it is still believed to be a mechanically driven disease, the role of underlying co-existing inflammatory processes and mediators in the onset of OA and its progression is now more appreciated. …"

A systematic review of literature on Insulin‐like growth factor‐2‐mediated hypoglycaemia in non‐islet cell tumours حسب Fateen Ata (12217764)

"…<h3>Introduction</h3><p dir="ltr">Insulin‐like growth factor‐2 (IGF‐2)‐mediated hypoglycemia is a rare yet clinically significant entity with considerable morbidity and mortality. …"

Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk حسب Merhi, Mahmoud

"…Background The role of inflammation in coronary artery disease (CAD) pathogenesis is well recognized. Moreover, smoking inhalation increases the activity of inflammatory mediators through an increase in leukotriene synthesis essential in atherosclerosis pathogenesis. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27–Driven Itch Pathway حسب Yanqing, Li

"…Chronic itch is a common and complex symptom often associated with skin diseases such as atopic dermatitis (AD). Although IL-27 is linked to AD, its role and clinical significance in itch remain undefined. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients حسب Alessandro Giuseppe Fois (2901365)