A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation حسب Zreik, Tony

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"

Investigating the acoustic release of doxorubicin from targeted micelles حسب Husseini, Ghaleb

"…The maximum amount of release (14%) was measured at 5.4 W/cm². A power density threshold at approximately 0.55 W/cm² exists below which no statistically significant release was observed. …"
احصل على النص الكامل

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed حسب Bartholomew, Aaron

احصل على النص الكامل

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy حسب Hamed Elgendy (14148846)

Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment حسب Mohammad, Najla

احصل على النص الكامل

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant حسب Lei Zhang (38117)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"

Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment حسب Amal Sabouni (17046236)

"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression حسب Rached, Johnny

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Facile Ultrasound-Triggered Release of Calcein and Doxorubicin from Iron-Based Metal-Organic Frameworks حسب Ibrahim, Mihad

"…However, there is a scarcity of studies on the uptake and release of guest molecules associated with MOF nanovehicles, and their mechanism is poorly understood. …"
احصل على النص الكامل

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

Comparative study of LNG, liquid hydrogen, and liquid ammonia post-release evaporation and dispersion during bunkering حسب Hongjun Fan (1388040)

"…Two release scenarios were considered: Scenario 1 involved a release of 0.3 m³ of fuel, and Scenario 2 involved a release of 100 kg of fuel. …"

Ultrasound-induced doxorubicin release from folate-targeted and non-targeted P105 micelles: a modeling study حسب Martins, Ana M.

"…The parameter λ, which is associated with the initial phase of the release process, showed a constant value regardless of the power density. …"
احصل على النص الكامل

Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis حسب Ahmed Fouad Algendy (18102706)

"…<h3>Objective</h3><p dir="ltr">The main aim is to compare the risk of severe hypoglycemia associated with the modified-release (MR) gliclazide against glimepiride in diabetic older adults. …"

Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... حسب Masri, Oussama Samer

"…Purpose Establishing the reliability of a new method to check the mean retinal and choroidal reflectivity and using it to find retinal and choroid changes in amblyopia. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Large scale association analysis identifies three susceptibility loci for coronary artery disease حسب El-Khazen, Georges

"…This approach replicated HNRNPA3P1-CXCL12 association with CAD and identified new significant associations of CDKAL1, ST6GAL1, and PTPRD with CAD. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل