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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Preoccupation with Weight and Eating Patterns of Lebanese and Cypriot Female Students
منشور في 2012"…This comparative cross-cultural study explores the prevalence of preoccupation with weight and eating patterns among female university students in two distinct cultural contexts, Cyprus and Lebanon. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Pattern of Postoperative Mortality After Esophageal Cancer Resection According to Center Volume
منشور في 2015"…The aim of this study was to define the pattern of POM and major morbidity in relation to center procedural volume. …"
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Blue collar laborers’ travel pattern recognition: Machine learning classifier approach
منشور في 2021"…Furthermore, whilst the Bagged Clusters and Pamk Clusters techniques on the three attributes yielded similar results, the Cmeans Clusters differed significantly in a number of the clusters. Applying such pattern recognition models on big and complex activity datasets could assist transport planners to understand the travel needs of segments of the population well and formulating better-informed strategies.…"
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Invasive Species as Rivals: Invasive Potential and Distribution Pattern of Xanthium strumarium L.
منشور في 2022"…<p dir="ltr">Xanthium strumarium L. is a globally successful invasive herb that has had significant negative ecological, economic and social impacts in many world regions. …"
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Impact of Resection Status on Pattern of Failure and Survival After Pancreaticoduodenectomy for Pancreatic Adenocarcinoma
منشور في 2007"…Objective: To better understand the impact of a microscopically positive margin (R1) on patterns of disease recurrence and survival after pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Characterizing the dynamics of climate and native desert plants in Qatar
منشور في 2024"…By analyzing Landsat satellite images from 1985 to 2022 and their relation to rainfall patterns, we found significant impacts of climatic variables on vegetation coverage, particularly after 1990. …"
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The outcome of severe traumatic brain injury in children in Qatar: Six-year study
منشور في 2015"…Among our patients 43.1% had spasticity, 33.8% experienced posttraumatic epilepsy. Better outcomes were observed after severe TBI among older children. …"
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Prediction of pressure gradient for oil-water flow: A comprehensive analysis on the performance of machine learning algorithms
منشور في 2022"…A total of eleven hundred experimental data points for nine FPs (two stratified and seven dispersed patterns) in horizontal wellbores are used to develop the MLs. …"
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