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يعرض 1 - 20 نتائج من 436 نتيجة بحث عن '(( significantly elevated expression ) OR ( significantly increased decrease ))', وقت الاستعلام: 0.08s تنقيح النتائج
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

    منشور في 2019
    "…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

    منشور في 2014
    "…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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    article
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    Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells حسب Shebaby, Wassim N.

    منشور في 2014
    "…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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    article
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    Circulating and Tumor-Infiltrating Immune Checkpoint-Expressing CD8+ Treg/T Cell Subsets and Their Associations with Disease-Free Survival in Colorectal Cancer Patients حسب Alhasan Alsalman (14802873)

    منشور في 2022
    "…We found that FoxP3 expression and ICs including PD-1, CTLA-4, TIM-3, and LAG-3 were significantly increased in tumor-infiltrating CD8+ T cells compared with NT and peripheral blood. …"
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    Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models حسب Mezher, Nawal

    منشور في 2025
    "…In this study, immunohistochemistry of colon samples from UC patients revealed significantly elevated expression and nuclear localization of ACSS2 in inflamed tissues compared to non-inflamed regions, suggesting its involvement in IBD pathogenesis. …"
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    masterThesis
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    Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis حسب Allgayer, Heike

    منشور في 2002
    "…The primary tumor-to-normal mucosa ratios of activity were compared following classification and regression tree (CART) analysis to determine the prognostic significance of elevated specific Src activity. Expression of u-PAR was correlated with Src activity. …"
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    Immunoprofile of childhood diabetes حسب Meritxell Espino-Guarch (15430868)

    منشور في 2023
    "…When transcriptomic data was interrogated, an imbalance between ITGA4/ ITGB1 was observed in all groups where CD49d showed increased expression. Associated with these findings, anti-inflammatory Treg cytokines including IL-10 were decreased in T2D patients and elevated plasma levels of IL-17, which contributes to the insulin resistance and inflammation were observed.…"
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    Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

    منشور في 2023
    "…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …"
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    Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats حسب Ines Fki (14571855)

    منشور في 2020
    "…The hepatic immunohistochemical analysis revealed a significant increase in the expression of inflammatory genes (COX-2, NF-<em>κ</em>B, and TNF-<em>α</em>). …"
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    Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity حسب Ayman Alzu’bi (13162392)

    منشور في 2025
    "…AB-FUBINACA treatment also causes a significant dose related decrease in sperm viability. …"
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    Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002) حسب Berberi, Rania

    منشور في 2002
    "…On the other hand, a 3% alcohol consumption (as beer or whisky) maintained for a two months period did not have an effect on fasting plasma TAG concentration while total and LDL cholesterol concentrations showed a significant decrease and HDL cholesterol concentration was moderately increased. …"
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    masterThesis
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    Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats حسب Daher, Costantine F.

    منشور في 2015
    "…A significant increase in serum blood glucose level was observed with hydroxycut intake in the presence of a high-fat diet. …"
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    article
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