Enoxaparin 20 mg for thromboprophylaxis in severe renal impairment حسب Karaoui, Lamis R.

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Profiling the autoantibody repertoire reveals autoantibodies associated with mild cognitive impairment and dementia حسب Hanan Ehtewish (17149825)

"…And 20 proteins had significantly altered autoantibody responses in MCI compared to cognitively normal individuals. …"

Accessibility first: detecting frustration in web browsing for visually impaired and sighted smartphone users حسب Yasmin Abdelaal (17773458)

"…<p dir="ltr">Smartphone adoption has become increasingly prevalent in modern society, reflecting the widespread integration of these devices into various aspects of daily life, yet accessibility and usability problems persist. …"

COVID-19 mothers’ mother–baby bonding, feeding practices, postnatal care experiences in Qatar: A mixed-methods approach حسب laura Moya falcon (22556218)

"…</p><h3>Conclusions</h3><p dir="ltr">The pandemic has significantly impacted maternal–infant bonding, as evidenced by increased reports of maternal stress, reduced physical contact, and limitations on partner support. …"

Prevalence and risk of cognitive impairment among patients with asthma: A systematic review and meta‐analysis حسب Ganesh Bushi (19709574)

"…The pooled prevalence of cognitive impairment in patients with asthma was 16.3%. The analysis also revealed an increased hazard ratio of 1.47 (95% confidence interval [1.09; 1.84]) for cognitive impairment in patients with asthma compared to the control group (individuals without asthma). …"

Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury حسب Judith, Nwaiwu

"…Results showed that while WD significantly increased fat percentage and elevated plasma cholesterol, there was no change in blood glucose level or body weight, indicating an early stage of MetS. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line حسب Toutounji, Mohamad

"…The present study investigates endoplasmic reticulum (ER) stress in addition to alterations in protein and membrane trafficking in a dextran sulfate sodium (DSS)-induced IBD-like phenotype of intestinal Caco-2 cells in culture. DSS treatment significantly reduced the transepithelial electric resistance (TEER) and increased the epithelial permeability of Caco-2 cells, without affecting their viability. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

High phosphorus diet mitigates impairments in lipid and glucose metabolism associated with diet-induced obesity in male sprague dawley rats حسب Bassil, Maya

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes حسب Hoda, Gad

"…AimCardiac autonomic neuropathy (CAN) has been suggested to be associated with hypoglycemia and impaired hypoglycemia unawareness. We have assessed the relationship between CAN and extensive measures of glucose variability (GV) in patients with type 1 and type 2 diabetes. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes حسب Hoda Gad (6470522)

"…The percentage GRADEEuglycemia (3.30 ± 2.78 vs. 5.69 ± 3.09, P = 0.017) and GRADEHypoglycemia (0.3 (range: 0 – 3.80) vs. 1.8 (range: 0.9–6.5), P = 0.036) were significantly lower, while the percentage median GRADEHyperglycemia (95.45 (range:93–98) vs. 91.6 (82.8–95.1), P = 0.013) was significantly higher in participants with CAN compared to those without CAN.…"

Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... حسب Masri, Oussama Samer

"…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Here, we aimed to understand the mechanisms underlying the impairment of pancreatic islet development and subsequent hypoplasia due to loss-of-function mutations in <i>RFX6</i>.…"

Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv... حسب Abdoulaye Diane (14152749)

"…Interestingly, addition of Exendin-4 (50 nM) during the last 3 days of the differentiation significantly enhanced GSIS associated with increased expression of glucose-sensing apparatus genes (Glut2, G6P2C, GCK) and genes encoding mitochondrial oxidative phosphorylation machinery.…"

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension حسب Thiruveni Ramkumar (17075051)

"…On the other hand, neonates of hypertensive mothers administered with methyldopa showed a significant decrease of initial blood glucose reading.…"

Rescue cerclage حسب Khoury, Alfred

"…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals حسب Angy, Mallah

"…Knowledge scores were higher among nurses holding a graduate degree (mean = 85; p < 0.05), and those who attended a training course (mean = 79; p < 0.05). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Qatar’s immigrants at higher risk of diabetes حسب Nature Research (16552612)

"…The results, however, suggest that Qatar’s immigrant population has a significantly increased risk of having undiagnosed T2D, and that glycated haemoglobin levels could be a useful diagnostic tool for early detection of the disease. …"

Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained? حسب Wahiba Elhag (5245547)

"…Mean HbA1c significantly decreased from 8.1%preop to 6.77%_{year 9}. …"

Sex differences on quality of life and mental health outcomes when using a brief cognitive-behavioral skill building intervention with adolescent Syrian refugees: a secondary analy... حسب Kazandjian, Chant

"…Among males only, significant decreases in depression and anxiety scores were observed with significant improvement in total QOL.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death حسب Tohme, Sara

"…Studying expression levels of regulatory proteins involved in iron homeostasis (FTH1, NCOA4 and DMT1/SLC11A2) and oxidative stress defense (NRF2, KEAP1, AIFM2/FSP1, 4f2hc/CD98, xCT/SLC7A11, and GPX4) suggests altered iron distribution and impaired antioxidant system in treated cells. Overall, these findings provide evidence that arginine deprivation induced by [HuArgI(Co)-PEG5000] leads to increased ROS production, lipid peroxidation, and dysregulation of iron metabolism and antioxidant pathways, all of which are hallmarks for the occurrence of ferroptosis in AML cells following arginine deprivation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل