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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Discourse Analysis of Lexical Cohesive Devices in Shakespearean Sonnets: Exploring their Significant Functions and Roles in ESL Poetry Classes
منشور في 2024"…Moreover, the research reveals how these devices contribute to creating contrast and tension, adding specificity and detail, illustrating relationships between components, enhancing descriptive detail, and establishing symmetry within the sonnets. The findings underscore the pedagogical significance of understanding and teaching cohesive devices in poetry writing. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Network Analysis and its Applications in Financial and Digital Assets
منشور في 2025احصل على النص الكامل
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Application of Data Mining to Predict and Diagnose Diabetic Retinopathy
منشور في 2024احصل على النص الكامل
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Scatter search for protein structure prediction. (c2008)
منشور في 2008احصل على النص الكامل
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A Testing Framework for Blockchain-Based Energy Trade Microgrids Applications
منشور في 2024"…This study suggests executing such a testing within a framework that integrates a Geographic Information System (GIS) environment with an Agent-Based Modeling (ABM) simulation platform. …"
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The use of multi-task learning in cybersecurity applications: a systematic literature review
منشور في 2024"…Despite government and corporate efforts, cybersecurity remains a significant concern. The application of multi-task learning (MTL) in cybersecurity is a promising solution, allowing security systems to simultaneously address various tasks and adapt in real-time to emerging threats. …"
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Just-in-time defect prediction for mobile applications: using shallow or deep learning?
منشور في 2023"…<p dir="ltr">Just-in-time defect prediction (JITDP) research is increasingly focused on program changes instead of complete program modules within the context of continuous integration and continuous testing paradigm. …"
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications
منشور في 2025"…Kinetic studies showed superior correlation with the pseudo-second-order model (R<sup>2</sup> > 0.996), with rate constants decreasing systematically from 767.5 to 216.0 g/mg·min as concentration increased, suggesting secondary chemical interactions may also contribute to the overall mechanism. …"
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MDPF: Minimum Distance Packet Forwarding for Search Applications in Mobile Ad Hoc Networks
منشور في 2009"…This paper introduces a message forwarding algorithm for search applications within mobile ad hoc networks that is based on the concept of selecting the nearest node from a set of designated nodes. …"
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article