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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Calculation of Average Road Speed Based on Car-to-Car Messaging
منشور في 2019"…Solutions based on geo-distributed road monitoring, using Fog-computing paradigm, provide lower latency and higher accuracy than centralized (cloud-based) approaches. …"
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Assessment of four dose calculation algorithms using IAEA-TECDOC-1583 with medium dependency correction factor (K<sub>med</sub>) application
منشور في 2024"…</p><h3>Results</h3><p dir="ltr">Average modelled correction factors for D<sub>m.m</sub>calculations using the farmer chamber are 0.976 (±0.1 %) for 6 MV and 0.979 (±0.1 %) for 15 MV in bone media. …"
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Exploring the Significance of Publication-Age-Based Parameters for Evaluating Researcher Impact
منشور في 2023"…In addition, these indices are often evaluated using dissimilar datasets, making it challenging to accurately compare their contributions and significance. …"
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On the molecular properties of graphene-pyrazines conjugated Ru and Fe complexes: Computational insights
منشور في 2020"…Graphene and related materials can exhibit substantial molecular properties of significant importance in various landscapes of interests including catalysis. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Validation of the geometric equivalent field concept in total scatter factor calculations, for half‐, quarter‐ and off‐isocenter asymmetric square fields
منشور في 2023"…</p><h2>Conclusions</h2><p dir="ltr">The GESF concept provides acceptable accuracy (< 2%) for the calculation of S<sub>cp</sub> of the ASFs used in most clinical situations (except from SOF with EFC at large r), and thus can be used in MU verification calculations.…"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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On the molecular properties of graphene-pyrazines conjugated Ru and Fe complexes: Computational insights
منشور في 2021"…<p dir="ltr">Graphene and related materials can exhibit substantial molecular properties of significant importance in various landscapes of interests including catalysis. …"
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Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines
منشور في 2022"…Additionally, applying the Chou-Talalay method using the CompuSyn software, the combination indexes (CI) were calculated to predict the interaction between CBD and the chemotherapeutic agents. …"
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