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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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The Environmental and Economic Impacts of the Use of Recycled Asphalt during the Preventive Maintenance of Roadway in the UAE.
منشور في 2023"…Furthermore, the economic influences which have been obtained from using recycled asphalt pavement in roadway maintenance are evaluated by the comparison of three scenarios by life cycle cost analysis with consideration of the analysis for 20 years. …"
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Effect of resonator location and boundary conditions on bandgap formation in a locally resonant beam metastructure
منشور في 2025"…The steady-state response of the structure, subjected to a concentrated harmonic load, is then computed using the modal analysis. Four different boundary conditions are considered. …"
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A framework based on an input-yield model for greenhouse optimisation for varying environmental conditions
منشور في 2024"…Moreover, parametric analysis demonstrates that greenhouse temperature and CO<sub>2</sub> have the most significant impact on the yield. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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ASSESMENT OF STRUCTURAL ELEMENTS DETERIORATED IN SEMI ARID ENVIRONMENTAL CONDITIONS
منشور في 2022"…The assessment and the interpretation using statistical analysis and modelling of the structure along with design helps to understand the effect of deterioration on structural elements in semi-arid environmental conditions.…"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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A novel integrated wastewater recovery, clean water production and air-conditioning system
منشور في 2021"…The consequence of this high energy and water demand are significant greenhouse gas emissions and other pollutants. …"
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Biochar yield prediction using response surface methodology: effect of fixed carbon and pyrolysis operating conditions
منشور في 2023"…An empirical equation is developed based on a statistically significant quadratic model to produce optimized biochar yield with high prediction accuracy. …"