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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Dexmedetomidine for improved quality of emergence from general anesthesia
منشور في 2017"…During emergence, cough, agitation, hemodynamic parameters, shivering, time to extubation, and sedation scores were recorded.A total of 190 patients were analyzed. …"
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A New Method for Generalizing Burr and Related Distributions
منشور في 2022"…In this method, the exponent of the Burr distribution is modeled using a nonlinear function of the data and one additional parameter. The models of this newly introduced generalized Burr family can significantly increase the flexibility of the former Burr distribution with respect to the density and hazard rate shapes. …"
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Pathloss and Time Dispersion Parameters for Indoor UWB propagation
منشور في 2006"…Site-specific trends and general observations are discussed. The results for path-loss exponent and time dispersion parameters are presented.…"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Path-loss and time dispersion parameters for indoor UWB propagation
منشور في 2006"…Site-specific trends and general observations are discussed. The results for path-loss exponent and time dispersion parameters are presented.…"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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The Russia-Ukraine war, soaring food prices, and the Turkish economy: insights from computable general equilibrium
منشور في 2023"…In this research paper, we examine the economic impact of war-induced soaring food prices on the Turkish economy using a Computable General Equilibrium (CGE) model, which is a widely used tool for simulating the effects of shocks and policy changes on a country’s economy. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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