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mirna expression » gene expression (توسيع البحث)
increased » increase (توسيع البحث)
decrease » increase (توسيع البحث)
mirna expression » gene expression (توسيع البحث)
increased » increase (توسيع البحث)
decrease » increase (توسيع البحث)
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miRNA-dependent regulation of STIM1 expression in breast cancer
منشور في 2019"…In contrast, STIM1 expression in the more aggressive basal triple-negative MDA-MB-231 cell line is not significantly modulated by a single miRNA species but is rather upregulated due to inhibition of the miRNA machinery through downregulation of Ago2. …"
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Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
منشور في 2024"…We aimed to identify distinctive expression patterns of circulating EV-miRNAs in AIS patients. …"
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Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
منشور في 2024"…We aimed to identify distinctive expression patterns of circulating EV-miRNAs in AIS patients. …"
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iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes
منشور في 2023"…To identify differentially expressed miRNAs (DEmiRs), and genes (DEGs), two differentFOXA2<sup>–</sup>/<sup>–</sup>iPSC lines were differentiated into PPs.FOXA2<sup>–</sup>/<sup>–</sup>PPs showed a significant reduction in the expression of the main PP transcription factors (TFs) in comparison to WT-PPs. …"
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iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes
منشور في 2023"…For differentially expressed miRNAs, a fold-change of >2 with a P-value <0.05 was used as a cutoff to determine the differentially expressed miRNAs in FOXA2–/–hiPSCs versus WT-hiPSCs. …"
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Gene Expression and miRNAs Profiling: Function and Regulation in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
منشور في 2019"…This review focuses on recent advances on gene expression and miRNA status in HER2-positive breast cancer.…"
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Expression of microRNA in follicular fluid in women with and without PCOS
منشور في 2019"…<p>Several studies have shown the expression of small non-coding microRNA (miRNA) changes in PCOS and their expression in follicular fluid has been described, though the number of studies remains small. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Anti-Angiogenic Effects of Phytochemicals on miRNA Regulating Breast Cancer Progression
منشور في 2020"…<p dir="ltr">Several phytochemicals have been identified for their role in modifying miRNA regulating tumor progression. miRNAs modulate the expression of several oncogenes and tumor suppressor genes including the genes that regulate tumor angiogenesis. …"
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MicroRNA Expression Profiling on Paired Primary and Lymph Node Metastatic Breast Cancer Revealed Distinct microRNA Profile Associated With LNM
منشور في 2020"…In current study, we performed comprehensive miRNA profiling in matched primary breast and LNM and identified 40 miRNAs, which were differentially expressed in LNM compared to primary tumors. …"
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Identifying miRNA Signatures Associated with Pancreatic Islet Dysfunction in a FOXA2-Deficient iPSC Model
منشور في 2024"…Furthermore, the absence of FOXA2 in iPSC-derived pancreatic islets resulted in significant alterations in miRNA expression, with 61 miRNAs upregulated and 99 downregulated. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Exploring the Fecal miRNA Profile in FMF Patients and the Role of miR-21-5p in Inflammatory Pathways Associated with FMF Pathogenesis
منشور في 2025"…Results: Among the 27 analyzed miRNAs, eight miRNAs were significantly higher in FMF patients compared to controls, with mir-21-5p, mir-30e-3p, and mir-148a-3p being specific to FMF patients. …"
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masterThesis -
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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